Fig. 4

PDK1 was a target for miR-210 in HAECs. a miR-210 expression levels in HAECs with miR-210 mimics, miR-210 inhibitor or null control (Null) transfection were detected via RT-qPCR. b The binding site of miR-210 to the 3′-UTR of PDK1 was calculated through bioinformatics analysis. c Relative luciferase activities with the wild-type or mutant 3′-UTR of PDK1 were quantified. d The effect of miR-210 on PDK1 expression was examined via qRT-PCR and western blot. *p < 0.05