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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: RNF7 inhibits apoptosis and sunitinib sensitivity and promotes glycolysis in renal cell carcinoma via the SOCS1/JAK/STAT3 feedback loop

Fig. 1

RNF7 expression is upregulated in ccRCC and is correlated with poor survival in patients with ccRCC. A RNF7 mRNA expression levels in ccRCC tissues (T, n = 533) and adjacent nontumor tissues (N, n = 72) from the TCGA database. B Comparison of RNF7 mRNA expression in ccRCC tissues (T, n = 20) and paired adjacent nontumor tissues (N, n = 20) from patients in hospital cohort 1. C, D Immunohistochemistry staining for RNF7 in ccRCC tissues (T, n = 158) and adjacent nontumor tissues (N, n = 20) from patients in hospital cohort 2. Scale bar: 50 µm. Survival probability of patients with ccRCC from (E) the TCGA database and (F) hospital cohort 2. Experiments performed in triplicate; data expressed as mean ± SD

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