Fig. 6

Lifestyle modifications and pharmacological interventions are strategies to combat aging and cellular senescence. Optimizing lifestyle with appropriate diet, exercise, sleep, and no smoking and pollution is critical to avoiding aging and cellular senescence. Pharmacological interventions by metformin, resveratrol, curcumin, statins, antioxidants, mTOR inhibitors, sirtuins activators, caloric restriction mimetics, and probiotics are also suggested as anti-aging remedies. Activate, inhibit