Fig. 6
From: SESN2 prevents the slow-to-fast myofiber shift in denervated atrophy via AMPK/PGC-1α pathway
SESN2 activated AMPK/PGC-1α signaling in denervated muscle. A Dynamic monitoring of AMPK/PGC-1α signaling in GAS post-denervation. B Western blot analysis confirming the regulatory effect of SESN2 on the activity of AMPK/PGC-1α signaling. Data presented as mean ± SD. n = 6. *P < 0.05 versus control (week 0 or sham operation group). #P < 0.05 versus denervation group. Den denervation, Con control