Fig. 1From: Three-dimensional genome landscape comprehensively reveals patterns of spatial gene regulation in papillary and anaplastic thyroid cancers: a study using representative cell lines for each cancer typeA–C Spatial proximity of co-mutated gene pairs. Violin plots of the contact frequency distribution of the TAD with various levels of CoMut (high), somatic filtering criteria or on background of gene level or overall level in A ATC (8305c), B PTC (BCPAP) and C PTC (TPC-1) cells, based on Hi-C data. D–I Spatial proximity of co-mutated gene pairs in TAD. The contact frequency distribution of various CoMut hotspot mutation counts in TAD in (D) ATC (8305c), (E) PTC (BCPAP), and (F) PTC (TPC-1) cells, based on Hi-C data; the contact frequency scatter plot on various CoMut hotspot mutation counts in (G) ATC (8305c), (H) PTC (BCPAP), and (I) PTC (TPC-1) cells based on Hi-C dataBack to article page