Fig. 2

Hypoxia and reoxygenation increased apoptosis and autophagy of HK-2 cells. Representative images A and statistical results B of HK-2 cells apoptosis and autophagy among different groups (original magnification ×200). CThe expression of miR-92a. Using Western blotting, representative band and statistical analysis D of LC3B II/I, Beclin 1, pJNK, JNK, MEK4, and active caspase 3 expression. *P < 0.05. Con control, DAPI 4′,6-diamidino-2-phenylindole, GAPDH glyceraldehyde phosphate dehydrogenase, GFP green fluorescent protein, hypo hypoxia, JNK c-Jun NH (2) terminal kinase, LC3B microtubule-associated protein 1 light chain 3B, MEK4 mitogen-activated protein kinase, pJNK phosphorylated JNK, Reo reoxygenation, RFP red fluorescent protein