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Fig. 6 | Cellular & Molecular Biology Letters

Fig. 6

From: PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo

Fig. 6

Effect of BLM on lethality and pulmonary fibrosis in mice. Lung fibrosis was induced in mice by intratracheal administration of BLM (5 mg/kgBW in 50 μL PBS) for 21 days. A Analysis of mouse mortality. B Mouse body temperature. C Body weight of mice. D Serum TGF-β1 levels in mice were estimated by ELISA. E Degree of pulmonary fibrosis in mice as determined by H&E staining. F The kidney, liver, and spleen samples of mice analysed by H&E staining. *, p < 0.05; **, p < 0.01; ***, p < 0.001. BLM bleomycin, PBS phosphate-buffered saline, TGF-β1 transforming growth factor β1, ELISA enzyme-linked immunosorbent assay, H&E haematoxylin and eosin

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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