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Fig. 8 | Cellular & Molecular Biology Letters

Fig. 8

From: PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo

Fig. 8

Expression of the PI3K/Akt and JNK/Smad signalling pathways-related proteins in mouse lung tissues. Lung fibrosis was induced in mice by intratracheal administration of BLM (5 mg/kgBW in 50 μL PBS) for 21 days. A Expression of the PI3K/Akt and JNK/Smad signalling pathways-related proteins in mouse lung tissues as determined by western blotting. B–E Quantitative analysis of the data presented in panel A. *, p < 0.05; **, p < 0.01; ***, p < 0.001. PI3K phosphoinositide 3-kinase, Akt protein kinase B, JNK c-Jun N-terminal kinase, Smad small of mothers against decapentaplegic, PBS phosphate-buffered saline

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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