Skip to main content
Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice

Fig. 2

Downregulation of CEBPB alleviates LN in mice. MRL/lpr mice were further treated with sh-NC or sh-CEBPB. A Immunohistochemical detection of CEBPB in the kidney tissues of mice. B Detection of CEBPB expression in kidney tissues of mice by RT–qPCR. C CEBPB expression in macrophages of mouse kidney tissues detected by dual-labeled immunofluorescence. D The creatinine levels in the serum of mice. E The ratio of urine protein to creatinine in mice. F The relative content of dsDNA in the serum of mice. G The IgG deposition in the kidney of mice. H C3 content in the serum of mice. I Histopathological analysis of kidney tissues of mice by HE staining. J PAS-positive deposition in the kidney tissues of mice. Data are presented as means ± SD (n = 8, *p < 0.05). Data were statistically analyzed using one-way ANOVA

Back to article page

Cellular & Molecular Biology Letters

ISSN: 1689-1392

Contact us