Fig. 3
From: The pyroptosis mediated biomarker pattern: an emerging diagnostic approach for Parkinson’s disease
Non-coding RNA levels in all participants. The expression levels of miR-675-5p (A), miR-1247-5p (C), circSLC8A1 (E), and lncH19 (G) were measured by RT-qPCR. The delta-delta cycle threshold value (2-ΔΔCt) method was used to analyze the results relative to the internal parameters, and the results were compared with the age-matched healthy control cohort (PD, n = 104; Ctl, n = 106). The midline in the box and whisker plots depicts the median, with upper and lower limits representing maximum and minimum values. ROC curve analysis of miR-675-5p (B), miR-1247-5p (D), circSLC8A1 (F), and lncH19 (H) relative to healthy controls (PD, Parkinson disease; Ctl, control; miR, microRNA; circ, circular RNA; lnc, long-noncoding RNA; ROC, receiver operating characteristic; *P < 0.05;**P < 0.01; ****P < 0.0001)