Fig. 5
From: The pyroptosis mediated biomarker pattern: an emerging diagnostic approach for Parkinson’s disease
Pyroptosis proteins and non-coding RNAs in the subset of PD patients. Mean expression levels of HMGB1 (A), IL-1β (B), IL-18 (C), GSDME (D), GSDME-N (E) and cleaved caspase3(F) were determined by ELISA and relative to the control cohort (PD, n = 70; Ctl, n = 54). The midline in the box and whisker plots depicts the median, with upper and lower limits representing maximum and minimum values. Correlation analysis between miR-1247-5p with cleaved caspase3, HMGB1 (G); circSLC8A1 with GSDME, IL-18, and HMGB1 expression levels (H) and shaded areas represent 95% confidence intervals (Ctl, control; PD, Parkinson patients; miR, microRNA; circ, circular RNA; lnc, long non-coding RNA; *P < 0.05)