Fig. 5
From: Molecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration
Co-IP/MS analysis determines HDAC9-interacting proteins in NP cells. A The NP cells isolated from C57BL/6J mice were subjected to co-IP/MS using anti-HDAC9 and IgG. B, C The protein identification results from database screening and the percentage of specific HDAC9-interacting proteins in NP cells. D The number of HDAC9-interacting proteins possibly modified by acetylation (611), phosphorylation (705), and ubiquitination (893) shown according to the PhosphoSitePlus database. E Eukaryotic Ortholog Groups (KOG) of proteins annotation of HDAC9-interacting proteins. F The number of HDAC9-interacting proteins that function as transcription factors in mice (36) and humans (80). G Lollipop plot presented the 34 common transcription factors in the classified 16 transcription factor families (Lollipop plot was drawn using https://www.chiplot.online/). H, I GO annotations determined the molecular functions of the HDAC9-interacting proteins