Table 1 EEF1A2 expression in cancer tissue and normal tissue, and its biological significance
From: Oncogenic activation of EEF1A2 expression: a journey from a putative to an established oncogene
Cancer type | EEF1A2 expression | Biological significance | References | |
|---|---|---|---|---|
Cancer tissue (No. of samples) | Normal tissue (No. of samples) | |||
Ovarian cancer | High (159/500) | NA | No change in prognosis | [17] |
None, low, moderate (341/500) | Serous tumors with high EEF1A2 expression show good prognosis | |||
Ovarian cancer | High (3/148) | NA | NA | [32] |
Moderate (7/148) | ||||
Low (49/148) | ||||
None (89/148) | ||||
Ovarian cancer | High (10/10) compared with benign endometriosis | NA | NA | [33] |
Breast cancer | High (79/380) | NA | Good prognosis | [18] |
Moderate (177/380) | Good prognosis | |||
Low (76/380) | ||||
None (48/380) | ||||
Breast cancer | High (5/46) | Low (7/7) | NA | [34] |
Moderate (22/46) | ||||
Low (19/46) | ||||
Triple-negative breast cancer | High (3/84) | NA | Poor prognosis | [35] |
Moderate (11/84) | ||||
Low (48/84) | ||||
None (22/84) compared with adjacent tissue | ||||
Prostate cancer | High (3/4) | None (1/1) | NA | [14] |
None (1/4) | ||||
Prostate cancer | High compared with adjacent normal tissue (26/30) | NA | NA | [36] |
Prostate cancer | High (40/40) compared with benign tumor (8/8) | NA | Poor prognosis | [19] |
Non-small cell lung cancer | High (58/69) compared with adjacent normal tissue of 46 patients | NA | Good prognosis | [38] |
Lung adenocarcinoma | High compared with adjacent normal tissue (32/113) | NA | Poor prognosis | [16] |
Lung adenocarcinoma | High compared with adjacent normal tissue (78/78) | NA | Poor prognosis | [37] |
Pancreatic cancer | High (41/62) | NA | NA | [7] |
Pancreatic ductal adenocarcinoma | High (76/97) | NA | Poor prognosis | [15] |
Pancreatic cancer | High (29/35) | No expression (8/8) | NA | [42] |
Chronic pancreatitis shows no expression (13/13) | ||||
Hepatocellular carcinoma | High (30/100) | None or very weak (27/27) | NA | [45] |
Moderate (24/100) | Adjacent normal tissue (84), high (1/84), moderate (14/84), weak (52/84), none (17/84) | |||
Weak (29/100) | ||||
None (17/100) | ||||
Hepatocellular carcinoma | High (24/48) | NA | Poor prognosis | [12] |
Low (24/48) | NA | Good prognosis | ||
Hepatocellular carcinoma | High (47/62) | None (20/20) | NA | [53] |
Paired pericarcinomatous | High (5/62) | |||
Gastric cancer | High (105/129) | Weak (9/24) | Poor prognosis | [46] |
None (15/24) | ||||