Fig. 3

Differentially expressed tsRNAs in the hyperplastic intima of rat carotid artery. A The abundance of tsRNAs and miRNAs was evaluated by their sequencing counts and were normalized as counts per million of total aligned reads (CPM). The top 15 up- and down-regulated tsRNAs in hyperplasic intima were listed based on their statistical significance, CPM, and expression change (fold change). B–E The expression differences of tRF-49:69-chrM.Trp-TCA, tRF-1:29-Glu-CTC-1, tRF-1:29-Gly-GCC-2-M2 and tRF-1:28-Gly-CCC-M2 in the sham surgery group and the balloon injury group were verified by qPCR. Their expression was all upregulated in the balloon injury group except for tRF-1:29-Gly-GCC-2-M2 by qPCR. n = 3, data are expressed as mean ± standard error, *P < 0.05, **P < 0.01, ns indicates for not statistically significant