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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Fig. 2

Profile of Circle-seq data for eccDNAs. A The volcano plot of differentially expressed eccDNA in the serum of newly diagnosed T2DM patients and NC subjects. B The top 42 upregulated circulating eccDNAs in T2DM patients compared with NC subjects. C Five upregulated eccDNAs were selected to validate using qPCR with the outward facing primers. D The 10 most enriched KEGG pathways in T2DM patients based on eccDNAs carrying genes

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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