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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Fig. 3

Serum eccDNA SORBS1circle level is increased in newly diagnosed T2DM patients. A Visualization of the most significantly upregulated serum eccDNA SORBS1circle. The junction site of eccDNA SORBS1circle was TCTG. B Gel electrophoresis images of validated serum eccDNA SORBS1circle. C qPCR validation of serum eccDNA SORBS1circle level in serum obtained from 106 newly diagnosed T2DM patients and 40 NC subjects. **P < 0.01. D ROC curves for the capacity of the serum eccDNA SORBS1circle to differentiate T2DM patients from NC subjects

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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