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Table 2 Correlation and regression analysis between serum eccDNA SORBS1circle level and other clinical and biochemical parameters

From: Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Varibles

Pearson correlation

Multiple linear regression

R value

P value

β value

T value

P value

Age

− 0.015

0.880

   

Sex

− 0.069

0.484

   

BMI

0.123

0.211

   

SBP

0.014

0.888

   

DBP

− 0.011

0.913

   

FBG

0.351

0.000**

0.079

1.124

0.264

2 hPBG

0.177

0.069

0.109

1.692

0.094

HbA1c

0.257

0.008**

0.141

2.193

0.031*

FIns

0.629

0.000**

− 0.069

− 0.544

0.588

2 hPIns

0.059

0.548

   

HOMA-IR

0.751

0.000**

0.751

11.593

0.000**

HOMA-β

0.177

0.069

− 0.067

− 0.982

0.329

TC

0.073

0.458

   

TG

0.106

0.278

   

HDL-C

− 0.091

0.354

   

LDL-C

− 0.003

0.978

   

ALT

0.005

0.962

   

AST

− 0.023

0.819

   

Cr

− 0.025

0.798

   

UA

− 0.153

0.117

   
  1. *P < 0.05, **P < 0.01. BMI Body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, 2 hPBG 2-h postprandial blood glucose, HbA1c glycosylated hemoglobin A1c, FIns fasting insulin, 2 hPIns 2-h postprandial insulin, HOMA-IR homeostasis model assessment of insulin resistance, HOMA-β homeostasis model assessment of islet β-cell function, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ALT alanine transaminase, AST aspartate transaminase, Cr creatinine, UA uric acid