Fig. 1

FFAR4 expression is significantly decreased in LUAD. A FFAR4 levels in different tumors were assessed using TCGA database. B The median expression of FFAR4 between normal and tumor samples in bodymap from the GEPIA. C Tumor tissue and control tissue samples in TCGA database were compared for FFAR4 expression. D A comparison of FFAR4 expression between normal tissue samples from GTEx and control and normal tissue samples from TCGA database was performed using WRST. E–F Analysis of GEO-GSE40275 and GEO-GSE118370 datasets confirms the presence of FFAR4 mRNA deregulation in LUAD. G–H Expression of FFAR4 mRNA in lung adenocarcinoma and paracarcinoma tissues of 11 patients with LUAD from the First Affiliated Hospital of Ningbo University. Data are expressed as the mean ± SEM. P < 0.05 was considered statistically significant using two-way analysis of variance (ANOVA); NS, not significant