Fig. 4

Feature gene selection. A, B Signature gene expression was screened based on the support vector machine recursive feature elimination (SVM-RFE) algorithm. C, D Adjusting feature selection using the least absolute shrinkage and selection operator (LASSO) algorithm. E Random forest error rate versus the number of classified trees. F The top 20 key genes. G Venn diagram of the six hub genes obtained from the intersection of results from SVM-RFE, RF, and LASSO algorithms