Fig. 4

circMAST1 suppresses tumor growth and metastasis in CCa via regulating YAP in vivo. A The image of dissected tumors from nude mice transplanted with stably overexpressed circMAST1 CCa cells or circMAST1 overexpression/YAP overexpression cells. B Subcutaneous tumor growth curves of mice in different treatment groups. C The mean weight of tumors upon sacrifice in the experimental groups. D, E Representative images of enucleated popliteal LNs (D) and histogram analysis of the LN volume (E) in the indicated cells. F Representative images of IF as indicators of LN status. G Quantification of metastatic area of popliteal LN metastasis in the indicated groups