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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: N6-methyladenosine-modified circ_104797 sustains cisplatin resistance in bladder cancer through acting as RNA sponges

Fig. 7

circRNA_104797 sustains cisplatin resistance by acting as a miRNA sponge for miR-103a and miR-660-3p. A Diagrammatic representation of the luciferase reporter vectors for wild-type (WT) and mutant (MUT) circ_104797; B, C luciferase activity measurements for both WT and MUT linear circ_104797 post-transfection with miR-103a (B) and miR-660-3p (C) mimics in cisplatin-resistant BCa cells; D, E post-demethylation of circ_104797 via CRISPR/dCas13b-ALKBH5, RT-qPCR was conducted to determine the expression levels of miR-103a and miR-660-3p in T24/CDDP (D) and 5637/CDDP (E) cells

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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