Fig. 7
From: The ancestral type of the R-RAS protein has oncogenic potential
Both sponge and human R-RAS2 homologs display oncogenic properties in MDA-MB-231 cells. A cell proliferation, B number of colonies formed, C wound healing, and D cell migration was quantified using the ImageJ software (National Institutes of Health, USA). The statistical significance of the tests was set at *p < 0.05, **p < 0.01, ***p < 0.001. The experiments were repeated three times in biological duplicates. Esu-sponge Eunapius subterraneus, Hsa-human