Fig. 4
From: MRE11A: a novel negative regulator of human DNA mismatch repair
MRE11A is recruited to chromatin by MMR proteins. A Representative western blotting of chromatin proteins coprecipitated with MSH2 12 h after DMSO or 200 nM MNNG treatment. B, C Representative western blotting of the chromatin binding MSH2, MLH1, and MRE11A proteins after knockdown of MSH2, MLH1, and MRE11A independently. The right graphs show the quantification of the western blotting bands relative to siNC controls. Data shown as mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001, using unpaired two-tailed Student’s t test