Fig. 2

Downregulation of circ-SLC16A1 inhibited the proliferation ability of NSCLC cells. A RT-qPCR detection showed the expression of circ-SLC16A1 in BEAS-2B, A549, and H1833 cells. Data shown as mean ± SD. ***P < 0.001 versus BEAS-2B. B RT-qPCR detection showed the expression of circ-SLC16A1 in both A549 and H1833 cells after transfection with siRNA against circ-SLC16A1. C–F Flow cytometry for cell cycle detection. Data shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 versus NC. G and H CCK8 detection showed the proliferation ability of both A549 and H1833 cells. Data shown as mean ± SD. ***P < 0.001 versus NC. I and J Clone formation showed the proliferation ability in both A549 and H1833 cells. Data shown as mean ± SD. **P < 0.01, ***P < 0.001 versus NC. K and L EdU detection showed the proliferation ability in both A549 and H1833 cells. Data shown as mean ± SD. *P < 0.05, **P < 0.01 versus NC