Fig. 2

P110 alleviates ischemic AKI and Inflammatory response in mice. A Representative images of H&E staining, KIM-1,NGAL and F4/80 immunohistochemistry. Scale bar = 50 μm. B Serum creatinine and BUN measurement. C Pathological score of tubular damage, Quantification of KIM-1,NGAL and F4/80 positive tubules. D Representative Immunoblot and quantitative analysis of IL-1β,MCP-1 and F4/80 in renal.β-actin was used as loading control. E q-PCR analysis of IL-1β, IL-6 and TNF-α. Quantitative data are expressed as mean ± SD (n = 5–8). *P < 0.05 versus respective Sham group; ^#P < 0.05 versus IR group