Fig. 3

P110 enhances mitochondrial recovery and cell proliferation. A Representative images of Ki67 immunofluorescence and PGC-1α and Cox I immunohistochemistry. Scale bar = 50 μm. B Quantification of Ki67 and Cox I positive tubules. C Representative Immunoblot and quantitative analysis of PGC-1α,SIRT3 and TFAM.β-actin was used as a loading control. D q-PCR analysis of Sirt3,Pgc1α and Nampt. Quantitative data are expressed as mean ± SD (n = 5). *P < 0.05 versus respective Sham group; ^#P < 0.05 versus IR group