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Fig. 9 | Cellular & Molecular Biology Letters

Fig. 9

From: Inhibition of Drp1- Fis1 interaction alleviates aberrant mitochondrial fragmentation and acute kidney injury

Fig. 9

P110 alleviates ischemic AKI and inflammation in Bama pigs. A Representative images of H&E staining, PAS staining and TUNEL staining, Scale bar = 50 µm. B Pathological score of tubular damage and Quantitative analysis of apoptotic cell numbers per mm square of kidney tissue. C The serum creatinine level. D The BUN level. D Representative Immunoblot and quantitative analysis of cGAS,p-TBK1,p-p65 and p-IRF3 in Bama pigs kidney tissue. Quantitative data represent the relative ratio to total TBK1 or p65 or IRF3. Cyclophilin B (CycB) was used as loading control.Quantitative data are expressed as mean ± SD. *P < 0.05 versus respective Sham group; #P < 0.05 versus IR group

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