Fig. 3
Downregulation of miR-192 in lung tissues and alveolar macrophages during obesity, further decreased following LPS stimulation. A RT-qPCR assessment of miR-192 levels in lung tissues of 8 obese and 4 control patients. B Pearson correlation between the relative expression of miR-192 and iNOS in lung tissues of obese patients (R2 = 0.6307, P = 0.0186). C Pearson correlation between the relative expression of miR-192 and TNF-α in lung tissues of obese patients (R2 = 0.7019, P = 0.0094). D, E RT-qPCR assessment of miR-192 levels in mouse lung tissues and AMs. F RT-qPCR assessment of miR-192 levels in MH-S cells. Data are expressed as the mean ± SD, *P < 0.05. **P < 0.01. ***P < 0.001. ****P < 0.0001