Open Access

The antioxidant properties of carnitine in vitro

  • Katarzyna Solarska1,
  • Anna Lewińska1,
  • Agata Karowicz-Bilińska2 and
  • Grzegorz Bartosz1, 3Email author
Cellular & Molecular Biology LettersAn International Journal200915:90

DOI: 10.2478/s11658-009-0036-y

Received: 23 May 2009

Accepted: 16 November 2009

Published: 20 November 2009

Abstract

Many of the effects of carnitine are ascribed to its antioxidant properties. The aim of this study was to evaluate the antioxidant properties of carnitine in vitro. Carnitine was found to decolorize ABTS•+, and to protect fluorescein against bleaching induced by AAPH-derived peroxyl radicals and peroxynitrite, thiol groups against oxidation induced by hydrogen peroxide, peroxyl radicals, hypochlorite and peroxynitrite, and erythrocytes against hemolysis induced by peroxyl radicals and hypochlorite. These results show that carnitine has a direct antioxidant action against physiologically relevant oxidants.

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