Skip to main content
Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: WNT5A–ROR2 is induced by inflammatory mediators and is involved in the migration of human ovarian cancer cell line SKOV-3

Fig. 4

Involvement of NF-kB and STAT3 signaling pathways in inflammation-induced Wnt5A expression. SKOV-3 cells treated with inflammatory mediators alone or in combination with BAY11-7082 as an NF-kB inhibitor or S31-201 as a STAT3 inhibitor for 24 h. LPS (a) and LTA (b). The upper panels show normalized values (means ± SD) from three independent western blots for Wnt5A expression for the indicated times. The lower panels represent one of three independent western blot analysis of Wnt5A. c – rhIL-6, with the left panel showing normalized values (means ± SD) from three independent western blots for Wnt5A expression for the indicated times and the right panel representing one of three independent western blot analyses of Wnt5A. GAPDH levels were used as the internal control. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001 as compared with the control (Ctrl)

Back to article page