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Table 1 Differentiation of cis- and trans-asRNAs

From: Natural antisense RNAs as mRNA regulatory elements in bacteria: a review on function and applications

cis-asRNAs trans-asRNAs
Also known as cis-NATs or cis effector asRNAs Also known as trans-NATs or trans effector asRNAs
Transcribed from the opposing DNA strand of the target gene at the same genomic locus Transcribed from a separate locus to the target gene
Display perfect or extensive sequence complementarity with the target gene Display imperfect or short stretches of complementarity with the target gene
Target individual mRNAs Target multiple sense targets and form complex regulation networks
Mostly short Frequently longer: several hundred nt, in some examples several kb long