From: Nuclear and nucleolar activity of linker histone variant H1.0
Physic-chemical and structural features | Attributes of intrinsic disorder |
---|---|
Amino acid compositiona | Enriched aa: Ala (14.9Â %), Lys (28.9Â %) |
Depleted aa: Asp (2.1Â %), Glu (2.6Â %), Phe (1.1Â %) | |
Grand average hydrophobicityb | Negative (score −1.073) |
Disorder degreec | Ratio – 0.62; disordered aa – 120/whole aa – 194 |
Domain disorder levelc | N- and C- – 100 %, Globular – 0 % |
Long disordered regionsd | Score – 0.8153, threshold score – 0.5380 |
MoRFs contente | Three elements (6, 9 and 10 aa) |
ANCHOR binding regionsf | Seven elements (12, 11, 14, 9, 18, 6 and 55 aa) |
Low-complexity regionsg | 18 aa N-/86 aa C- |