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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: Posttranscriptional and transcriptional regulation of endothelial nitric-oxide synthase during hypoxia: the role of microRNAs

Fig. 2

The ER stress induced dynamic changes in the mRNA of the NOS3 that are negatively correlated with CHOP expression in human umbilical vein endothelial cells (HUVECs). The ER stress was induced with 100 μM Calpain Inhibitor I (ALLN). mRNA levels were monitored in qRT-PCR experiments as described in [106, 107]. The results from 2 independent experiments (n = 8) are plotted normalized to TBP mRNA levels and expressed as a fold-change over the untreated control. Error bars represent standard deviations. Significant changes (p < 0.05) are marked with an “*”

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