Fig. 1

Schematic representation of the domain structure of BAG family proteins. All six reported BAG proteins contain a BAG domain at their C-terminus. The BAG2 C-terminal domain is defined as the BNB domain. There is a coiled coil domain near the amino terminus. Domains in the other BAG-family proteins include a nuclear localization signal (NLS), ubiquitin-like (UBL) domain, WW domain, DUF domain, and proline-rich regions (PXXP)