Fig. 2
From: Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator
a The distribution of optimal and rare codons in CFTR. The logarithm transformed moving median of RSCU values (3-amino acid window) suggests the presence of slow/nonoptimal (negative log RSCU values) and fast/optimal (positive) translated patches within the CFTR primary structure. The amino acid medians were normalized to whole CFTR median RSCU (value 1). The CFTR domain location is marked above the graph. b CFTR domains are translated with different rates as shown by their median RSCU values. The domain medians were normalized to whole CFTR median RSCU (value 1). Significantly faster (>1) and slower (<1) translation of the domains are marked with an *, while error bars represent the standard error of the mean (SEM)