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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: miR-378 suppresses the proliferation, migration and invasion of colon cancer cells by inhibiting SDAD1

Fig. 4

SDAD1 is a direct target of miR-378. a The complementary sequences of the miR-378 binding site in SDAD1 3’UTR. The sequence of mutated SDAD1 3’UTR is also shown. b The effect of miR-378 on luciferase intensity controlled by the wild type (Wt) or mutant (Mut) 3’UTR of SDAD1 was determined using the luciferase assay. c, d The mRNA (C) and protein (D) levels of SDAD1 were detected using quantitative RT-PCR and western blot, respectively, in SW480 cells transfected with miR-378 mimics. *p < 0.05, **p < 0.01, ns: not significant

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