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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: Gene functioning and storage within a folded genome

Fig. 3

A scheme illustrating two proposal mechanisms of TAD boundary action. Left panel: boundary plays an active role in TAD demarcation preventing interdomain interactions. Right panel: boundary represents a genomic region unable to fold into higher-order structures and/or to interact with adjacent regions. In contrast, TAD is comprised of chromatin regions which tend to interact with each other forming globular structures

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