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Table 2 The number and positions of E-box hexanucleotide consensus sequence (CANNTG) in OCT4 transcription unit

From: Ectopic expression of TWIST1 upregulates the stemness marker OCT4 in the esophageal squamous cell carcinoma cell line KYSE30

Sequence

Number

Positions

CACTTG

8

506–511, 4882–4887, 5233–5238, 5573–5578, 8676–8681, 12,560–12,565, 13,578–13,583, 15,856–15,861

CAGGTG

13

1160–1165,1527–1532,2430–2435,2951–2956*,3435–3440,3773–3778,4067–4072,6173–6178,10,155–10,160*, 10,695–10,700,14,196–14,201*,14,380–14,385*,15,862–15,867*

CAAGTG

8

1283–1288,1518–1523,10,518–10,523,11,353–11,358,13,240–13,245,13,593–13,598*,13,613–13,618*,14,154–14,159*

CATCTG

2

2013–2018,15,053–15,058

CAGCTG

11

2180–2185,2951–2956*,4829–4834,5708–5713,6782–6787*,7763–7768,7939–7944,9308–9313,9488–9493,10,593–10,598,10,635–10,640

CACCTG

15

2239–2244,3538–3543,3926–3921,4010–4015,4998–5003,6898–6903*,6922–6927*,9443–9448,10,121–10,126*,10,587–10,529,12,259–12,264,12,518–12,523,13,823–13,828*,15,348–15,353,15,435–15,440

CATTTG

4

2306–2311,4433–4438,11,264–11,269,14,514–14,519*

CATATG

3

2538–2543,6233–6238,11,855–11,860

CAGATG

5

2556–2561,5599–5604,5700–5705,9206–9211,11,951–11,956

CAGTTG

4

4390–4395,5737–5742,9884–9889,12,014–12,019

CAAATG

1

4397–4402

CACATG

2

4569–4574,5850–5855

CAACTG

6

4850–4855,6768–6773*,10,665–10,670,10,728–10,733,15,680–15,685,16,283–16,288*

CATGTG

2

5057–5062,15,092–15,097

CAATTG

1

11,487–11,492*

  1. The asterisks indicate exonic E-boxes