Fig. 2
From: Orally administered endoxifen inhibits tumor growth in melanoma-bearing mice
Therapeutic efficacy of endoxifen in the B16F10 melanoma tumor model in mice. Endoxifen or tamoxifen significantly reduced nodule counts when compared to the control group (p < 0.05). At an equal dose of 8 mg/kg body weight, endoxifen exhibited significantly stronger activity in reducing melanoma nodule counts than tamoxifen (p < 0.05). The data represent means ± SD, (n = 5)