TY - JOUR AU - Nylander, K. AU - Vojtesek, B. AU - Nenutil, R. AU - Lindgren, B. AU - Roos, G. AU - Zhanxiang, W. PY - 2002 DA - 2002// TI - Differential expression of p63 isoforms in normal tissues and neoplastic cells JO - J Pathol. VL - 198 UR - https://doi.org/10.1002/path.1231 DO - 10.1002/path.1231 ID - Nylander2002 ER - TY - JOUR AU - Nekulova, M. AU - Holcakova, J. AU - Nenutil, R. AU - Stratmann, R. AU - Bouchalova, P. AU - Müller, P. PY - 2013 DA - 2013// TI - Characterization of specific p63 and p63-N-terminal isoform antibodies and their application for immunohistochemistry JO - Virchows Arch. VL - 463 UR - https://doi.org/10.1007/s00428-013-1459-4 DO - 10.1007/s00428-013-1459-4 ID - Nekulova2013 ER - TY - JOUR AU - Orzol, P. AU - Nekulova, M. AU - Holcakova, J. AU - Muller, P. AU - Votesek, B. AU - Coates, P. J. PY - 2016 DA - 2016// TI - ΔNp63 regulates cell proliferation, differentiation, adhesion, and migration in the BL2 subtype of basal-like breast cancer JO - Tumour Biol. VL - 37 UR - https://doi.org/10.1007/s13277-016-4880-x DO - 10.1007/s13277-016-4880-x ID - Orzol2016 ER - TY - JOUR AU - Holcakova, J. AU - Nekulova, M. AU - Orzol, P. AU - Nenutil, R. AU - Podhorec, J. AU - Svoboda, M. PY - 2017 DA - 2017// TI - ΔNp63 activates EGFR signaling to induce loss of adhesion in triple-negative basal-like breast cancer cells JO - Breast Cancer Res Treat. VL - 163 UR - https://doi.org/10.1007/s10549-017-4216-6 DO - 10.1007/s10549-017-4216-6 ID - Holcakova2017 ER - TY - JOUR AU - Banerjee, K. AU - Resat, H. PY - 2016 DA - 2016// TI - Constitutive activation of STAT3 in breast cancer cells: A review JO - Int J Cancer. VL - 138 UR - https://doi.org/10.1002/ijc.29923 DO - 10.1002/ijc.29923 ID - Banerjee2016 ER - TY - JOUR AU - Carpenter, R. L. AU - Lo, H. W. PY - 2014 DA - 2014// TI - STAT3 Target Genes Relevant to Human Cancers JO - Cancers (Basel). VL - 6 UR - https://doi.org/10.3390/cancers6020897 DO - 10.3390/cancers6020897 ID - Carpenter2014 ER - TY - JOUR AU - Yu, H. AU - Pardoll, D. AU - Jove, R. PY - 2009 DA - 2009// TI - STATs in cancer inflammation and immunity: a leading role for STAT3 JO - Nat Rev Cancer. VL - 9 UR - https://doi.org/10.1038/nrc2734 DO - 10.1038/nrc2734 ID - Yu2009 ER - TY - JOUR AU - Nekulova, M. AU - Holcakova, J. AU - Coates, P. AU - Vojtesek, B. PY - 2011 DA - 2011// TI - The role of p63 in cancer, stem cells and cancer stem cells JO - Cell Mol Biol Lett. VL - 16 UR - https://doi.org/10.2478/s11658-011-0009-9 DO - 10.2478/s11658-011-0009-9 ID - Nekulova2011 ER - TY - JOUR AU - Orzol, P. AU - Holcakova, J. AU - Nekulova, M. AU - Nenutil, R. AU - Vojtesek, B. AU - Coates, P. J. PY - 2015 DA - 2015// TI - The diverse oncogenic and tumour suppressor roles of p63 and p73 in cancer: a review by cancer site JO - Histol Histopathol. VL - 30 ID - Orzol2015 ER - TY - JOUR AU - Avalle, L. AU - Camporeale, A. AU - Camperi, A. AU - Poli, V. PY - 2017 DA - 2017// TI - STAT3 in cancer: A double edged sword JO - Cytokine. VL - 98 UR - https://doi.org/10.1016/j.cyto.2017.03.018 DO - 10.1016/j.cyto.2017.03.018 ID - Avalle2017 ER - TY - JOUR AU - Bishop, J. A. AU - Teruya-Feldstein, J. AU - Westra, W. H. AU - Pelosi, G. AU - Travis, W. D. AU - Rekhtman, N. PY - 2012 DA - 2012// TI - p40 (ΔNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma JO - Mod Pathol. VL - 25 UR - https://doi.org/10.1038/modpathol.2011.173 DO - 10.1038/modpathol.2011.173 ID - Bishop2012 ER - TY - JOUR AU - Pellegrini, G. AU - Dellambra, E. AU - Golisano, O. AU - Martinelli, E. AU - Fantozzi, I. AU - Bondanza, S. PY - 2001 DA - 2001// TI - p63 identifies keratinocyte stem cells JO - Proc Natl Acad Sci U S A. VL - 98 UR - https://doi.org/10.1073/pnas.061032098 DO - 10.1073/pnas.061032098 ID - Pellegrini2001 ER - TY - JOUR AU - Memmi, E. M. AU - Sanarico, A. G. AU - Giacobbe, A. AU - Peschiaroli, A. AU - Frezza, V. AU - Cicalese, A. PY - 2015 DA - 2015// TI - p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling JO - Proc Natl Acad Sci U S A. VL - 112 UR - https://doi.org/10.1073/pnas.1500762112 DO - 10.1073/pnas.1500762112 ID - Memmi2015 ER - TY - JOUR AU - You, L. AU - Wang, Z. AU - Li, H. AU - Shou, J. AU - Jing, Z. AU - Xie, J. PY - 2015 DA - 2015// TI - The role of STAT3 in autophagy JO - Autophagy. VL - 11 UR - https://doi.org/10.1080/15548627.2015.1017192 DO - 10.1080/15548627.2015.1017192 ID - You2015 ER - TY - JOUR AU - Caldenhoven, E. AU - van Dijk, T. B. AU - Solari, R. AU - Armstrong, J. AU - Raaijmakers, J. A. AU - Lammers, J. W. PY - 1996 DA - 1996// TI - STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription JO - J Biol Chem. VL - 271 UR - https://doi.org/10.1074/jbc.271.22.13221 DO - 10.1074/jbc.271.22.13221 ID - Caldenhoven1996 ER - TY - JOUR PY - 2017 DA - 2017// TI - UniProt: the universal protein knowledgebase JO - Nucleic Acids Res. VL - 45 UR - https://doi.org/10.1093/nar/gkw1099 DO - 10.1093/nar/gkw1099 ID - ref16 ER - TY - JOUR AU - Schaefer, T. S. AU - Sanders, L. K. AU - Nathans, D. PY - 1995 DA - 1995// TI - Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3 JO - Proc Natl Acad Sci U S A. VL - 92 UR - https://doi.org/10.1073/pnas.92.20.9097 DO - 10.1073/pnas.92.20.9097 ID - Schaefer1995 ER - TY - JOUR AU - Maritano, D. AU - Sugrue, M. L. AU - Tininini, S. AU - Dewilde, S. AU - Strobl, B. AU - Fu, X. PY - 2004 DA - 2004// TI - The STAT3 isoforms alpha and beta have unique and specific functions JO - Nat Immunol. VL - 5 UR - https://doi.org/10.1038/ni1052 DO - 10.1038/ni1052 ID - Maritano2004 ER - TY - JOUR AU - Kato, T. AU - Sakamoto, E. AU - Kutsuna, H. AU - Kimura-Eto, A. AU - Hato, F. AU - Kitagawa, S. PY - 2004 DA - 2004// TI - Proteolytic conversion of STAT3alpha to STAT3gamma in human neutrophils: role of granule-derived serine proteases JO - J Biol Chem. VL - 279 UR - https://doi.org/10.1074/jbc.M400637200 DO - 10.1074/jbc.M400637200 ID - Kato2004 ER - TY - JOUR AU - Hevehan, D. L. AU - Miller, W. M. AU - Papoutsakis, E. T. PY - 2002 DA - 2002// TI - Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation JO - Blood. VL - 99 UR - https://doi.org/10.1182/blood.V99.5.1627 DO - 10.1182/blood.V99.5.1627 ID - Hevehan2002 ER - TY - JOUR AU - Nishiki, S. AU - Hato, F. AU - Kamata, N. AU - Sakamoto, E. AU - Hasegawa, T. AU - Kimura-Eto, A. PY - 2004 DA - 2004// TI - Selective activation of STAT3 in human monocytes stimulated by G-CSF: implication in inhibition of LPS-induced TNF-alpha production JO - Am J Physiol Cell Physiol. VL - 286 UR - https://doi.org/10.1152/ajpcell.00387.2003 DO - 10.1152/ajpcell.00387.2003 ID - Nishiki2004 ER - TY - JOUR AU - Rush, J. AU - Moritz, A. AU - Lee, K. A. AU - Guo, A. AU - Goss, V. L. AU - Spek, E. J. PY - 2005 DA - 2005// TI - Immunoaffinity profiling of tyrosine phosphorylation in cancer cells JO - Nat Biotechnol. VL - 23 UR - https://doi.org/10.1038/nbt1046 DO - 10.1038/nbt1046 ID - Rush2005 ER - TY - JOUR AU - Bian, Y. AU - Song, C. AU - Cheng, K. AU - Dong, M. AU - Wang, F. AU - Huang, J. PY - 2014 DA - 2014// TI - An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome JO - J Proteomics. VL - 96 UR - https://doi.org/10.1016/j.jprot.2013.11.014 DO - 10.1016/j.jprot.2013.11.014 ID - Bian2014 ER - TY - JOUR AU - Levy, D. E. AU - Darnell, J. E. PY - 2002 DA - 2002// TI - Stats: transcriptional control and biological impact JO - Nat Rev Mol Cell Biol. VL - 3 UR - https://doi.org/10.1038/nrm909 DO - 10.1038/nrm909 ID - Levy2002 ER - TY - JOUR AU - Fagard, R. AU - Metelev, V. AU - Souissi, I. AU - Baran-Marszak, F. PY - 2013 DA - 2013// TI - STAT3 inhibitors for cancer therapy: Have all roads been explored? JO - JAKSTAT. VL - 2 ID - Fagard2013 ER - TY - JOUR AU - Zhong, Z. AU - Wen, Z. AU - Darnell, J. E. PY - 1994 DA - 1994// TI - Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 JO - Science. VL - 264 UR - https://doi.org/10.1126/science.8140422 DO - 10.1126/science.8140422 ID - Zhong1994 ER - TY - JOUR AU - Darnell, J. E. AU - Kerr, I. M. AU - Stark, G. R. PY - 1994 DA - 1994// TI - Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins JO - Science. VL - 264 UR - https://doi.org/10.1126/science.8197455 DO - 10.1126/science.8197455 ID - Darnell1994 ER - TY - JOUR AU - Decker, T. AU - Kovarik, P. AU - Meinke, A. PY - 1997 DA - 1997// TI - GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression JO - J Interferon Cytokine Res. VL - 17 UR - https://doi.org/10.1089/jir.1997.17.121 DO - 10.1089/jir.1997.17.121 ID - Decker1997 ER - TY - STD TI - Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, et al. JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Res. 2017; ID - ref29 ER - TY - JOUR AU - Khatib, H. AU - Huang, W. AU - Mikheil, D. AU - Schutzkus, V. AU - Monson, R. L. PY - 2009 DA - 2009// TI - Effects of signal transducer and activator of transcription (STAT) genes STAT1 and STAT3 genotypic combinations on fertilization and embryonic survival rates in Holstein cattle JO - J Dairy Sci. VL - 92 UR - https://doi.org/10.3168/jds.2009-2439 DO - 10.3168/jds.2009-2439 ID - Khatib2009 ER - TY - JOUR AU - Decker, T. AU - Kovarik, P. PY - 1999 DA - 1999// TI - Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins JO - Cell Mol Life Sci. VL - 55 UR - https://doi.org/10.1007/s000180050393 DO - 10.1007/s000180050393 ID - Decker1999 ER - TY - JOUR AU - Gupta, M. AU - Han, J. J. AU - Stenson, M. AU - Maurer, M. AU - Wellik, L. AU - Hu, G. PY - 2012 DA - 2012// TI - Elevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation JO - Blood. VL - 119 UR - https://doi.org/10.1182/blood-2011-10-388538 DO - 10.1182/blood-2011-10-388538 ID - Gupta2012 ER - TY - JOUR AU - Ernst, M. AU - Najdovska, M. AU - Grail, D. AU - Lundgren-May, T. AU - Buchert, M. AU - Tye, H. PY - 2008 DA - 2008// TI - STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice JO - J Clin Invest. VL - 118 ID - Ernst2008 ER - TY - JOUR AU - Peterson, W. M. AU - Wang, Q. AU - Tzekova, R. AU - Wiegand, S. J. PY - 2000 DA - 2000// TI - Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia JO - J Neurosci. VL - 20 ID - Peterson2000 ER - TY - JOUR AU - Kunisada, K. AU - Hirota, H. AU - Fujio, Y. AU - Matsui, H. AU - Tani, Y. AU - Yamauchi-Takihara, K. PY - 1996 DA - 1996// TI - Activation of JAK-STAT and MAP kinases by leukemia inhibitory factor through gp130 in cardiac myocytes JO - Circulation. VL - 94 UR - https://doi.org/10.1161/01.CIR.94.10.2626 DO - 10.1161/01.CIR.94.10.2626 ID - Kunisada1996 ER - TY - JOUR AU - Yanagisawa, M. AU - Nakashima, K. AU - Taga, T. PY - 1999 DA - 1999// TI - STAT3-mediated astrocyte differentiation from mouse fetal neuroepithelial cells by mouse oncostatin M JO - Neurosci Lett. VL - 269 UR - https://doi.org/10.1016/S0304-3940(99)00447-4 DO - 10.1016/S0304-3940(99)00447-4 ID - Yanagisawa1999 ER - TY - JOUR AU - Wang, Y. AU - van Boxel-Dezaire, A. H. AU - Cheon, H. AU - Yang, J. AU - Stark, G. R. PY - 2013 DA - 2013// TI - STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor JO - Proc Natl Acad Sci U S A. VL - 110 UR - https://doi.org/10.1073/pnas.1315862110 DO - 10.1073/pnas.1315862110 ID - Wang2013 ER - TY - JOUR AU - Zhao, D. AU - Pan, C. AU - Sun, J. AU - Gilbert, C. AU - Drews-Elger, K. AU - Azzam, D. J. PY - 2015 DA - 2015// TI - VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2 JO - Oncogene. VL - 34 UR - https://doi.org/10.1038/onc.2014.257 DO - 10.1038/onc.2014.257 ID - Zhao2015 ER - TY - JOUR AU - Vignais, M. L. AU - Sadowski, H. B. AU - Watling, D. AU - Rogers, N. C. AU - Gilman, M. PY - 1996 DA - 1996// TI - Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins JO - Mol Cell Biol. VL - 16 UR - https://doi.org/10.1128/MCB.16.4.1759 DO - 10.1128/MCB.16.4.1759 ID - Vignais1996 ER - TY - JOUR AU - Zong, C. S. AU - Chan, J. AU - Levy, D. E. AU - Horvath, C. AU - Sadowski, H. B. AU - Wang, L. H. PY - 2000 DA - 2000// TI - Mechanism of STAT3 activation by insulin-like growth factor I receptor JO - J Biol Chem. VL - 275 UR - https://doi.org/10.1074/jbc.M000089200 DO - 10.1074/jbc.M000089200 ID - Zong2000 ER - TY - JOUR AU - Schreiner, S. J. AU - Schiavone, A. P. AU - Smithgall, T. E. PY - 2002 DA - 2002// TI - Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain JO - J Biol Chem. VL - 277 UR - https://doi.org/10.1074/jbc.M204255200 DO - 10.1074/jbc.M204255200 ID - Schreiner2002 ER - TY - JOUR AU - Coppo, P. AU - Flamant, S. AU - De Mas, V. AU - Jarrier, P. AU - Guillier, M. AU - Bonnet, M. L. PY - 2006 DA - 2006// TI - BCR-ABL activates STAT3 via JAK and MEK pathways in human cells JO - Br J Haematol. VL - 134 UR - https://doi.org/10.1111/j.1365-2141.2006.06161.x DO - 10.1111/j.1365-2141.2006.06161.x ID - Coppo2006 ER - TY - JOUR AU - Guryanova, O. A. AU - Wu, Q. AU - Cheng, L. AU - Lathia, J. D. AU - Huang, Z. AU - Yang, J. PY - 2011 DA - 2011// TI - Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3 JO - Cancer Cell. VL - 19 UR - https://doi.org/10.1016/j.ccr.2011.03.004 DO - 10.1016/j.ccr.2011.03.004 ID - Guryanova2011 ER - TY - JOUR AU - Kortylewski, M. AU - Kujawski, M. AU - Herrmann, A. AU - Yang, C. AU - Wang, L. AU - Liu, Y. PY - 2009 DA - 2009// TI - Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy JO - Cancer Res. VL - 69 UR - https://doi.org/10.1158/0008-5472.CAN-08-3031 DO - 10.1158/0008-5472.CAN-08-3031 ID - Kortylewski2009 ER - TY - JOUR AU - Eyking, A. AU - Ey, B. AU - Rünzi, M. AU - Roig, A. I. AU - Reis, H. AU - Schmid, K. W. PY - 2011 DA - 2011// TI - Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer JO - Gastroenterology. VL - 141 UR - https://doi.org/10.1053/j.gastro.2011.08.043 DO - 10.1053/j.gastro.2011.08.043 ID - Eyking2011 ER - TY - JOUR AU - Lee, H. AU - Deng, J. AU - Kujawski, M. AU - Yang, C. AU - Liu, Y. AU - Herrmann, A. PY - 2010 DA - 2010// TI - STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors JO - Nat Med. VL - 16 UR - https://doi.org/10.1038/nm.2250 DO - 10.1038/nm.2250 ID - Lee2010 ER - TY - JOUR AU - Lee, J. L. AU - Wang, M. J. AU - Chen, J. Y. PY - 2009 DA - 2009// TI - Acetylation and activation of STAT3 mediated by nuclear translocation of CD44 JO - J Cell Biol. VL - 185 UR - https://doi.org/10.1083/jcb.200812060 DO - 10.1083/jcb.200812060 ID - Lee2009 ER - TY - JOUR AU - Zheng, L. AU - Jia, X. AU - Zhang, C. AU - Wang, D. AU - Cao, Z. AU - Wang, J. PY - 2015 DA - 2015// TI - Angiotensin II in atrial structural remodeling: the role of Ang II/JAK/STAT3 signaling pathway JO - Am J Transl Res. VL - 7 ID - Zheng2015 ER - TY - JOUR AU - Geletu, M. AU - Arulanandam, R. AU - Chevalier, S. AU - Saez, B. AU - Larue, L. AU - Feracci, H. PY - 2013 DA - 2013// TI - Classical cadherins control survival through the gp130/Stat3 axis JO - Biochim Biophys Acta. VL - 1833 UR - https://doi.org/10.1016/j.bbamcr.2013.03.014 DO - 10.1016/j.bbamcr.2013.03.014 ID - Geletu2013 ER - TY - JOUR AU - Turkson, J. AU - Bowman, T. AU - Adnane, J. AU - Zhang, Y. AU - Djeu, J. Y. AU - Sekharam, M. PY - 1999 DA - 1999// TI - Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein JO - Mol Cell Biol. VL - 19 UR - https://doi.org/10.1128/MCB.19.11.7519 DO - 10.1128/MCB.19.11.7519 ID - Turkson1999 ER - TY - JOUR AU - Chung, J. AU - Uchida, E. AU - Grammer, T. C. AU - Blenis, J. PY - 1997 DA - 1997// TI - STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation JO - Mol Cell Biol. VL - 17 UR - https://doi.org/10.1128/MCB.17.11.6508 DO - 10.1128/MCB.17.11.6508 ID - Chung1997 ER - TY - JOUR AU - Lim, C. P. AU - Cao, X. PY - 1999 DA - 1999// TI - Serine phosphorylation and negative regulation of Stat3 by JNK JO - J Biol Chem. VL - 274 UR - https://doi.org/10.1074/jbc.274.43.31055 DO - 10.1074/jbc.274.43.31055 ID - Lim1999 ER - TY - JOUR AU - Jain, N. AU - Zhang, T. AU - Kee, W. H. AU - Li, W. AU - Cao, X. PY - 1999 DA - 1999// TI - Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner JO - J Biol Chem. VL - 274 UR - https://doi.org/10.1074/jbc.274.34.24392 DO - 10.1074/jbc.274.34.24392 ID - Jain1999 ER - TY - JOUR AU - Kim, J. H. AU - Yoon, M. S. AU - Chen, J. PY - 2009 DA - 2009// TI - Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation JO - J Biol Chem. VL - 284 UR - https://doi.org/10.1074/jbc.M109.051516 DO - 10.1074/jbc.M109.051516 ID - Kim2009 ER - TY - JOUR AU - Wen, Z. AU - Zhong, Z. AU - Darnell, J. E. PY - 1995 DA - 1995// TI - Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation JO - Cell. VL - 82 UR - https://doi.org/10.1016/0092-8674(95)90311-9 DO - 10.1016/0092-8674(95)90311-9 ID - Wen1995 ER - TY - JOUR AU - Zhang, X. AU - Blenis, J. AU - Li, H. C. AU - Schindler, C. AU - Chen-Kiang, S. PY - 1995 DA - 1995// TI - Requirement of serine phosphorylation for formation of STAT-promoter complexes JO - Science. VL - 267 UR - https://doi.org/10.1126/science.7701321 DO - 10.1126/science.7701321 ID - Zhang1995 ER - TY - JOUR AU - Shi, X. AU - Zhang, H. AU - Paddon, H. AU - Lee, G. AU - Cao, X. AU - Pelech, S. PY - 2006 DA - 2006// TI - Phosphorylation of STAT3 serine-727 by cyclin-dependent kinase 1 is critical for nocodazole-induced mitotic arrest JO - Biochemistry. VL - 45 UR - https://doi.org/10.1021/bi052490j DO - 10.1021/bi052490j ID - Shi2006 ER - TY - JOUR AU - Androutsellis-Theotokis, A. AU - Leker, R. R. AU - Soldner, F. AU - Hoeppner, D. J. AU - Ravin, R. AU - Poser, S. W. PY - 2006 DA - 2006// TI - Notch signalling regulates stem cell numbers in vitro and in vivo JO - Nature. VL - 442 UR - https://doi.org/10.1038/nature04940 DO - 10.1038/nature04940 ID - Androutsellis-Theotokis2006 ER - TY - JOUR AU - Liu, H. AU - Ma, Y. AU - Cole, S. M. AU - Zander, C. AU - Chen, K. H. AU - Karras, J. PY - 2003 DA - 2003// TI - Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival JO - Blood. VL - 102 UR - https://doi.org/10.1182/blood-2002-11-3396 DO - 10.1182/blood-2002-11-3396 ID - Liu2003 ER - TY - JOUR AU - Qin, H. R. AU - Kim, H. J. AU - Kim, J. Y. AU - Hurt, E. M. AU - Klarmann, G. J. AU - Kawasaki, B. T. PY - 2008 DA - 2008// TI - Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation JO - Cancer Res. VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-08-1125 DO - 10.1158/0008-5472.CAN-08-1125 ID - Qin2008 ER - TY - JOUR AU - Frank, D. A. AU - Mahajan, S. AU - Ritz, J. PY - 1997 DA - 1997// TI - B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues JO - J Clin Invest. VL - 100 UR - https://doi.org/10.1172/JCI119869 DO - 10.1172/JCI119869 ID - Frank1997 ER - TY - JOUR AU - Hazan-Halevy, I. AU - Harris, D. AU - Liu, Z. AU - Liu, J. AU - Li, P. AU - Chen, X. PY - 2010 DA - 2010// TI - STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells JO - Blood. VL - 115 UR - https://doi.org/10.1182/blood-2009-10-230060 DO - 10.1182/blood-2009-10-230060 ID - Hazan-Halevy2010 ER - TY - JOUR AU - Wegrzyn, J. AU - Potla, R. AU - Chwae, Y. J. AU - Sepuri, N. B. AU - Zhang, Q. AU - Koeck, T. PY - 2009 DA - 2009// TI - Function of mitochondrial Stat3 in cellular respiration JO - Science. VL - 323 UR - https://doi.org/10.1126/science.1164551 DO - 10.1126/science.1164551 ID - Wegrzyn2009 ER - TY - JOUR AU - Gough, D. J. AU - Corlett, A. AU - Schlessinger, K. AU - Wegrzyn, J. AU - Larner, A. C. AU - Levy, D. E. PY - 2009 DA - 2009// TI - Mitochondrial STAT3 supports Ras-dependent oncogenic transformation JO - Science. VL - 324 UR - https://doi.org/10.1126/science.1171721 DO - 10.1126/science.1171721 ID - Gough2009 ER - TY - JOUR AU - Liu, L. AU - McBride, K. M. AU - Reich, N. C. PY - 2005 DA - 2005// TI - STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3 JO - Proc Natl Acad Sci U S A. VL - 102 UR - https://doi.org/10.1073/pnas.0501643102 DO - 10.1073/pnas.0501643102 ID - Liu2005 ER - TY - JOUR AU - Cimica, V. AU - Chen, H. C. AU - Iyer, J. K. AU - Reich, N. C. PY - 2011 DA - 2011// TI - Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1 JO - PLoS One. VL - 6 UR - https://doi.org/10.1371/journal.pone.0020188 DO - 10.1371/journal.pone.0020188 ID - Cimica2011 ER - TY - JOUR AU - Butturini, E. AU - Gotte, G. AU - Dell'Orco, D. AU - Chiavegato, G. AU - Marino, V. AU - Canetti, D. PY - 2016 DA - 2016// TI - Intermolecular disulfide bond influences unphosphorylated STAT3 dimerization and function JO - Biochem J. VL - 473 UR - https://doi.org/10.1042/BCJ20160294 DO - 10.1042/BCJ20160294 ID - Butturini2016 ER - TY - JOUR AU - Timofeeva, O. A. AU - Chasovskikh, S. AU - Lonskaya, I. AU - Tarasova, N. I. AU - Khavrutskii, L. AU - Tarasov, S. G. PY - 2012 DA - 2012// TI - Mechanisms of unphosphorylated STAT3 transcription factor binding to DNA JO - J Biol Chem. VL - 287 UR - https://doi.org/10.1074/jbc.M111.323899 DO - 10.1074/jbc.M111.323899 ID - Timofeeva2012 ER - TY - JOUR AU - Nkansah, E. AU - Shah, R. AU - Collie, G. W. AU - Parkinson, G. N. AU - Palmer, J. AU - Rahman, K. M. PY - 2013 DA - 2013// TI - Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography JO - FEBS Lett. VL - 587 UR - https://doi.org/10.1016/j.febslet.2013.01.065 DO - 10.1016/j.febslet.2013.01.065 ID - Nkansah2013 ER - TY - JOUR AU - Yang, J. AU - Chatterjee-Kishore, M. AU - Staugaitis, S. M. AU - Nguyen, H. AU - Schlessinger, K. AU - Levy, D. E. PY - 2005 DA - 2005// TI - Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation JO - Cancer Res. VL - 65 ID - Yang2005 ER - TY - JOUR AU - Yang, J. AU - Liao, X. AU - Agarwal, M. K. AU - Barnes, L. AU - Auron, P. E. AU - Stark, G. R. PY - 2007 DA - 2007// TI - Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB JO - Genes Dev. VL - 21 UR - https://doi.org/10.1101/gad.1553707 DO - 10.1101/gad.1553707 ID - Yang2007 ER - TY - JOUR AU - Yuan, Z. L. AU - Guan, Y. J. AU - Chatterjee, D. AU - Chin, Y. E. PY - 2005 DA - 2005// TI - Stat3 dimerization regulated by reversible acetylation of a single lysine residue JO - Science. VL - 307 UR - https://doi.org/10.1126/science.1105166 DO - 10.1126/science.1105166 ID - Yuan2005 ER - TY - JOUR AU - Wang, R. AU - Cherukuri, P. AU - Luo, J. PY - 2005 DA - 2005// TI - Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation JO - J Biol Chem. VL - 280 UR - https://doi.org/10.1074/jbc.M413930200 DO - 10.1074/jbc.M413930200 ID - Wang2005 ER - TY - JOUR AU - Dasgupta, M. AU - Unal, H. AU - Willard, B. AU - Yang, J. AU - Karnik, S. S. AU - Stark, G. R. PY - 2014 DA - 2014// TI - Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3 JO - J Biol Chem. VL - 289 UR - https://doi.org/10.1074/jbc.M114.603894 DO - 10.1074/jbc.M114.603894 ID - Dasgupta2014 ER - TY - JOUR AU - Kim, E. AU - Kim, M. AU - Woo, D. H. AU - Shin, Y. AU - Shin, J. AU - Chang, N. PY - 2013 DA - 2013// TI - Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells JO - Cancer Cell. VL - 23 UR - https://doi.org/10.1016/j.ccr.2013.04.008 DO - 10.1016/j.ccr.2013.04.008 ID - Kim2013 ER - TY - JOUR AU - Su, F. AU - Ren, F. AU - Rong, Y. AU - Wang, Y. AU - Geng, Y. AU - Feng, M. PY - 2012 DA - 2012// TI - Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer JO - Breast Cancer Res. VL - 14 UR - https://doi.org/10.1186/bcr3134 DO - 10.1186/bcr3134 ID - Su2012 ER - TY - JOUR AU - Kumar, V. AU - Cheng, P. AU - Condamine, T. AU - Mony, S. AU - Languino, L. R. AU - McCaffrey, J. C. PY - 2016 DA - 2016// TI - CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation JO - Immunity. VL - 44 UR - https://doi.org/10.1016/j.immuni.2016.01.014 DO - 10.1016/j.immuni.2016.01.014 ID - Kumar2016 ER - TY - JOUR AU - Kim, D. J. AU - Tremblay, M. L. AU - Digiovanni, J. PY - 2010 DA - 2010// TI - Protein tyrosine phosphatases, TC-PTP, SHP1, and SHP2, cooperate in rapid dephosphorylation of Stat3 in keratinocytes following UVB irradiation JO - PLoS One. VL - 5 UR - https://doi.org/10.1371/journal.pone.0010290 DO - 10.1371/journal.pone.0010290 ID - Kim2010 ER - TY - JOUR AU - Zgheib, C. AU - Zouein, F. A. AU - Chidiac, R. AU - Kurdi, M. AU - Booz, G. W. PY - 2012 DA - 2012// TI - Calyculin A reveals serine/threonine phosphatase protein phosphatase 1 as a regulatory nodal point in canonical signal transducer and activator of transcription 3 signaling of human microvascular endothelial cells JO - J Interferon Cytokine Res. VL - 32 UR - https://doi.org/10.1089/jir.2011.0059 DO - 10.1089/jir.2011.0059 ID - Zgheib2012 ER - TY - JOUR AU - Lu, D. AU - Liu, L. AU - Ji, X. AU - Gao, Y. AU - Chen, X. AU - Liu, Y. PY - 2015 DA - 2015// TI - The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation JO - Nat Immunol. VL - 16 UR - https://doi.org/10.1038/ni.3278 DO - 10.1038/ni.3278 ID - Lu2015 ER - TY - JOUR AU - Yuan, J. AU - Zhang, F. AU - Niu, R. PY - 2015 DA - 2015// TI - Multiple regulation pathways and pivotal biological functions of STAT3 in cancer JO - Sci Rep. VL - 5 UR - https://doi.org/10.1038/srep17663 DO - 10.1038/srep17663 ID - Yuan2015 ER - TY - JOUR AU - Nicholson, S. E. AU - De Souza, D. AU - Fabri, L. J. AU - Corbin, J. AU - Willson, T. A. AU - Zhang, J. G. PY - 2000 DA - 2000// TI - Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130 JO - Proc Natl Acad Sci U S A. VL - 97 UR - https://doi.org/10.1073/pnas.100135197 DO - 10.1073/pnas.100135197 ID - Nicholson2000 ER - TY - JOUR AU - Lee, J. H. AU - Kim, C. AU - Sethi, G. AU - Ahn, K. S. PY - 2015 DA - 2015// TI - Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel JO - Oncotarget. VL - 6 ID - Lee2015 ER - TY - JOUR AU - Chung, C. D. AU - Liao, J. AU - Liu, B. AU - Rao, X. AU - Jay, P. AU - Berta, P. PY - 1997 DA - 1997// TI - Specific inhibition of Stat3 signal transduction by PIAS3 JO - Science. VL - 278 UR - https://doi.org/10.1126/science.278.5344.1803 DO - 10.1126/science.278.5344.1803 ID - Chung1997 ER - TY - JOUR AU - Yang, J. AU - Huang, J. AU - Dasgupta, M. AU - Sears, N. AU - Miyagi, M. AU - Wang, B. PY - 2010 DA - 2010// TI - Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes JO - Proc Natl Acad Sci U S A. VL - 107 UR - https://doi.org/10.1073/pnas.1016147107 DO - 10.1073/pnas.1016147107 ID - Yang2010 ER - TY - JOUR AU - Yu, H. AU - Lee, H. AU - Herrmann, A. AU - Buettner, R. AU - Jove, R. PY - 2014 DA - 2014// TI - Revisiting STAT3 signalling in cancer: new and unexpected biological functions JO - Nat Rev Cancer. VL - 14 UR - https://doi.org/10.1038/nrc3818 DO - 10.1038/nrc3818 ID - Yu2014 ER - TY - JOUR AU - Cai, B. AU - Li, J. AU - Wang, J. AU - Luo, X. AU - Ai, J. AU - Liu, Y. PY - 2012 DA - 2012// TI - microRNA-124 regulates cardiomyocyte differentiation of bone marrow-derived mesenchymal stem cells via targeting STAT3 signaling JO - Stem Cells. VL - 30 UR - https://doi.org/10.1002/stem.1154 DO - 10.1002/stem.1154 ID - Cai2012 ER - TY - JOUR AU - Jiang, J. AU - Li, Z. AU - Yu, C. AU - Chen, M. AU - Tian, S. AU - Sun, C. PY - 2015 DA - 2015// TI - MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer JO - Cancer Lett. VL - 356 UR - https://doi.org/10.1016/j.canlet.2014.11.007 DO - 10.1016/j.canlet.2014.11.007 ID - Jiang2015 ER - TY - JOUR AU - Zhang, H. AU - Cai, K. AU - Wang, J. AU - Wang, X. AU - Cheng, K. AU - Shi, F. PY - 2014 DA - 2014// TI - MiR-7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway JO - Stem Cells. VL - 32 UR - https://doi.org/10.1002/stem.1795 DO - 10.1002/stem.1795 ID - Zhang2014 ER - TY - JOUR AU - Pawlus, M. R. AU - Wang, L. AU - Hu, C. J. PY - 2014 DA - 2014// TI - STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells JO - Oncogene. VL - 33 UR - https://doi.org/10.1038/onc.2013.115 DO - 10.1038/onc.2013.115 ID - Pawlus2014 ER - TY - JOUR AU - Reya, T. AU - Morrison, S. J. AU - Clarke, M. F. AU - Weissman, I. L. PY - 2001 DA - 2001// TI - Stem cells, cancer, and cancer stem cells JO - Nature. VL - 414 UR - https://doi.org/10.1038/35102167 DO - 10.1038/35102167 ID - Reya2001 ER - TY - JOUR AU - Takahashi, K. AU - Yamanaka, S. PY - 2006 DA - 2006// TI - Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors JO - Cell. VL - 126 UR - https://doi.org/10.1016/j.cell.2006.07.024 DO - 10.1016/j.cell.2006.07.024 ID - Takahashi2006 ER - TY - JOUR AU - Humphrey, R. K. AU - Beattie, G. M. AU - Lopez, A. D. AU - Bucay, N. AU - King, C. C. AU - Firpo, M. T. PY - 2004 DA - 2004// TI - Maintenance of pluripotency in human embryonic stem cells is STAT3 independent JO - Stem Cells. VL - 22 UR - https://doi.org/10.1634/stemcells.22-4-522 DO - 10.1634/stemcells.22-4-522 ID - Humphrey2004 ER - TY - JOUR AU - Davis, S. AU - Aldrich, T. H. AU - Stahl, N. AU - Pan, L. AU - Taga, T. AU - Kishimoto, T. PY - 1993 DA - 1993// TI - LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor JO - Science. VL - 260 UR - https://doi.org/10.1126/science.8390097 DO - 10.1126/science.8390097 ID - Davis1993 ER - TY - JOUR AU - Matsuda, T. AU - Nakamura, T. AU - Nakao, K. AU - Arai, T. AU - Katsuki, M. AU - Heike, T. PY - 1999 DA - 1999// TI - STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells JO - EMBO J. VL - 18 UR - https://doi.org/10.1093/emboj/18.15.4261 DO - 10.1093/emboj/18.15.4261 ID - Matsuda1999 ER - TY - JOUR AU - Raz, R. AU - Lee, C. K. AU - Cannizzaro, L. A. AU - d'Eustachio, P. AU - Levy, D. E. PY - 1999 DA - 1999// TI - Essential role of STAT3 for embryonic stem cell pluripotency JO - Proc Natl Acad Sci U S A. VL - 96 UR - https://doi.org/10.1073/pnas.96.6.2846 DO - 10.1073/pnas.96.6.2846 ID - Raz1999 ER - TY - JOUR AU - Cartwright, P. AU - McLean, C. AU - Sheppard, A. AU - Rivett, D. AU - Jones, K. AU - Dalton, S. PY - 2005 DA - 2005// TI - LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism JO - Development. VL - 132 UR - https://doi.org/10.1242/dev.01670 DO - 10.1242/dev.01670 ID - Cartwright2005 ER - TY - JOUR AU - Chen, C. Y. AU - Lee, D. S. AU - Yan, Y. T. AU - Shen, C. N. AU - Hwang, S. M. AU - Lee, S. T. PY - 2015 DA - 2015// TI - Bcl3 Bridges LIF-STAT3 to Oct4 Signaling in the Maintenance of Naïve Pluripotency JO - Stem Cells. VL - 33 UR - https://doi.org/10.1002/stem.2201 DO - 10.1002/stem.2201 ID - Chen2015 ER - TY - JOUR AU - Torres, J. AU - Watt, F. M. PY - 2008 DA - 2008// TI - Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3 JO - Nat Cell Biol. VL - 10 UR - https://doi.org/10.1038/ncb1680 DO - 10.1038/ncb1680 ID - Torres2008 ER - TY - JOUR AU - Huang, G. AU - Yan, H. AU - Ye, S. AU - Tong, C. AU - Ying, Q. L. PY - 2014 DA - 2014// TI - STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ESC fates JO - Stem Cells. VL - 32 UR - https://doi.org/10.1002/stem.1609 DO - 10.1002/stem.1609 ID - Huang2014 ER - TY - JOUR AU - Gu, F. AU - Hata, R. AU - Ma, Y. J. AU - Tanaka, J. AU - Mitsuda, N. AU - Kumon, Y. PY - 2005 DA - 2005// TI - Suppression of Stat3 promotes neurogenesis in cultured neural stem cells JO - J Neurosci Res. VL - 81 UR - https://doi.org/10.1002/jnr.20561 DO - 10.1002/jnr.20561 ID - Gu2005 ER - TY - JOUR AU - Kamakura, S. AU - Oishi, K. AU - Yoshimatsu, T. AU - Nakafuku, M. AU - Masuyama, N. AU - Gotoh, Y. PY - 2004 DA - 2004// TI - Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling JO - Nat Cell Biol. VL - 6 UR - https://doi.org/10.1038/ncb1138 DO - 10.1038/ncb1138 ID - Kamakura2004 ER - TY - JOUR AU - Yoshimatsu, T. AU - Kawaguchi, D. AU - Oishi, K. AU - Takeda, K. AU - Akira, S. AU - Masuyama, N. PY - 2006 DA - 2006// TI - Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex JO - Development. VL - 133 UR - https://doi.org/10.1242/dev.02419 DO - 10.1242/dev.02419 ID - Yoshimatsu2006 ER - TY - JOUR AU - Chung, Y. J. AU - Park, B. B. AU - Kang, Y. J. AU - Kim, T. M. AU - Eaves, C. J. AU - Oh, I. H. PY - 2006 DA - 2006// TI - Unique effects of Stat3 on the early phase of hematopoietic stem cell regeneration JO - Blood. VL - 108 UR - https://doi.org/10.1182/blood-2006-01-010199 DO - 10.1182/blood-2006-01-010199 ID - Chung2006 ER - TY - JOUR AU - Zhu, H. AU - Xiao, F. AU - Wang, G. AU - Wei, X. AU - Jiang, L. AU - Chen, Y. PY - 2016 DA - 2016// TI - STAT3 Regulates Self-Renewal of Adult Muscle Satellite Cells during Injury-Induced Muscle Regeneration JO - Cell Rep. VL - 16 UR - https://doi.org/10.1016/j.celrep.2016.07.041 DO - 10.1016/j.celrep.2016.07.041 ID - Zhu2016 ER - TY - JOUR AU - Tadokoro, T. AU - Wang, Y. AU - Barak, L. S. AU - Bai, Y. AU - Randell, S. H. AU - Hogan, B. L. PY - 2014 DA - 2014// TI - IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells JO - Proc Natl Acad Sci U S A. VL - 111 UR - https://doi.org/10.1073/pnas.1409781111 DO - 10.1073/pnas.1409781111 ID - Tadokoro2014 ER - TY - JOUR AU - Yuan, Y. AU - Xi, Y. AU - Chen, J. AU - Zhu, P. AU - Kang, J. AU - Zou, Z. PY - 2017 DA - 2017// TI - STAT3 stimulates adipogenic stem cell proliferation and cooperates with HMGA2 during the early stage of differentiation to promote adipogenesis JO - Biochem Biophys Res Commun. VL - 482 UR - https://doi.org/10.1016/j.bbrc.2016.12.042 DO - 10.1016/j.bbrc.2016.12.042 ID - Yuan2017 ER - TY - JOUR AU - Chen, Q. AU - Quan, Y. AU - Wang, N. AU - Xie, C. AU - Ji, Z. AU - He, H. PY - 2017 DA - 2017// TI - Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea JO - Stem Cell Reports. VL - 9 UR - https://doi.org/10.1016/j.stemcr.2017.05.031 DO - 10.1016/j.stemcr.2017.05.031 ID - Chen2017 ER - TY - JOUR AU - Staniszewska, A. D. AU - Pensa, S. AU - Caffarel, M. M. AU - Anderson, L. H. AU - Poli, V. AU - Watson, C. J. PY - 2012 DA - 2012// TI - Stat3 is required to maintain the full differentiation potential of mammary stem cells and the proliferative potential of mammary luminal progenitors JO - PLoS One. VL - 7 UR - https://doi.org/10.1371/journal.pone.0052608 DO - 10.1371/journal.pone.0052608 ID - Staniszewska2012 ER - TY - JOUR AU - Dahéron, L. AU - Opitz, S. L. AU - Zaehres, H. AU - Lensch, M. W. AU - Lensch, W. M. AU - Andrews, P. W. PY - 2004 DA - 2004// TI - LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells JO - Stem Cells. VL - 22 UR - https://doi.org/10.1634/stemcells.22-5-770 DO - 10.1634/stemcells.22-5-770 ID - Dahéron2004 ER - TY - JOUR AU - Yang, J. AU - van Oosten, A. L. AU - Theunissen, T. W. AU - Guo, G. AU - Silva, J. C. AU - Smith, A. PY - 2010 DA - 2010// TI - Stat3 activation is limiting for reprogramming to ground state pluripotency JO - Cell Stem Cell. VL - 7 UR - https://doi.org/10.1016/j.stem.2010.06.022 DO - 10.1016/j.stem.2010.06.022 ID - Yang2010 ER - TY - JOUR AU - Chen, H. AU - Aksoy, I. AU - Gonnot, F. AU - Osteil, P. AU - Aubry, M. AU - Hamela, C. PY - 2015 DA - 2015// TI - Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency JO - Nat Commun. VL - 6 UR - https://doi.org/10.1038/ncomms8095 DO - 10.1038/ncomms8095 ID - Chen2015 ER - TY - JOUR AU - Matsui, F. AU - Babitz, S. A. AU - Rhee, A. AU - Hile, K. L. AU - Zhang, H. AU - Meldrum, K. K. PY - 2017 DA - 2017// TI - Mesenchymal stem cells protect against obstruction-induced renal fibrosis by decreasing STAT3 activation and STAT3-dependent MMP-9 production JO - Am J Physiol Renal Physiol. VL - 312 UR - https://doi.org/10.1152/ajprenal.00311.2016 DO - 10.1152/ajprenal.00311.2016 ID - Matsui2017 ER - TY - JOUR AU - Hsu, H. S. AU - Lin, J. H. AU - Hsu, T. W. AU - Su, K. AU - Wang, C. W. AU - Yang, K. Y. PY - 2012 DA - 2012// TI - Mesenchymal stem cells enhance lung cancer initiation through activation of IL-6/JAK2/STAT3 pathway JO - Lung Cancer. VL - 75 UR - https://doi.org/10.1016/j.lungcan.2011.07.001 DO - 10.1016/j.lungcan.2011.07.001 ID - Hsu2012 ER - TY - JOUR AU - Rattigan, Y. AU - Hsu, J. M. AU - Mishra, P. J. AU - Glod, J. AU - Banerjee, D. PY - 2010 DA - 2010// TI - Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu JO - Exp Cell Res. VL - 316 UR - https://doi.org/10.1016/j.yexcr.2010.07.002 DO - 10.1016/j.yexcr.2010.07.002 ID - Rattigan2010 ER - TY - JOUR AU - Buettner, R. AU - Mora, L. B. AU - Jove, R. AU - Activated, S. T. A. T. PY - 2002 DA - 2002// TI - signaling in human tumors provides novel molecular targets for therapeutic intervention JO - Clin Cancer Res. VL - 8 ID - Buettner2002 ER - TY - JOUR AU - Marotta, L. L. AU - Almendro, V. AU - Marusyk, A. AU - Shipitsin, M. AU - Schemme, J. AU - Walker, S. R. PY - 2011 DA - 2011// TI - The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors JO - J Clin Invest. VL - 121 UR - https://doi.org/10.1172/JCI44745 DO - 10.1172/JCI44745 ID - Marotta2011 ER - TY - JOUR AU - Forbes, S. A. AU - Beare, D. AU - Boutselakis, H. AU - Bamford, S. AU - Bindal, N. AU - Tate, J. PY - 2017 DA - 2017// TI - COSMIC: somatic cancer genetics at high-resolution JO - Nucleic Acids Res. VL - 45 UR - https://doi.org/10.1093/nar/gkw1121 DO - 10.1093/nar/gkw1121 ID - Forbes2017 ER - TY - JOUR AU - Xiong, H. AU - Du, W. AU - Wang, J. L. AU - Wang, Y. C. AU - Tang, J. T. AU - Hong, J. PY - 2012 DA - 2012// TI - Constitutive activation of STAT3 is predictive of poor prognosis in human gastric cancer JO - J Mol Med (Berl). VL - 90 UR - https://doi.org/10.1007/s00109-012-0869-0 DO - 10.1007/s00109-012-0869-0 ID - Xiong2012 ER - TY - JOUR AU - Mora, L. B. AU - Buettner, R. AU - Seigne, J. AU - Diaz, J. AU - Ahmad, N. AU - Garcia, R. PY - 2002 DA - 2002// TI - Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells JO - Cancer Res. VL - 62 ID - Mora2002 ER - TY - JOUR AU - Masuda, M. AU - Suzui, M. AU - Yasumatu, R. AU - Nakashima, T. AU - Kuratomi, Y. AU - Azuma, K. PY - 2002 DA - 2002// TI - Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma JO - Cancer Res. VL - 62 ID - Masuda2002 ER - TY - JOUR AU - Györffy, B. AU - Lanczky, A. AU - Eklund, A. C. AU - Denkert, C. AU - Budczies, J. AU - Li, Q. PY - 2010 DA - 2010// TI - An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients JO - Breast Cancer Res Treat. VL - 123 UR - https://doi.org/10.1007/s10549-009-0674-9 DO - 10.1007/s10549-009-0674-9 ID - Györffy2010 ER - TY - JOUR AU - Lánczky, A. AU - Nagy, Á. AU - Bottai, G. AU - Munkácsy, G. AU - Szabó, A. AU - Santarpia, L. PY - 2016 DA - 2016// TI - miRpower: a web-tool to validate survival-associated miRNAs utilizing expression data from 2178 breast cancer patients JO - Breast Cancer Res Treat. VL - 160 UR - https://doi.org/10.1007/s10549-016-4013-7 DO - 10.1007/s10549-016-4013-7 ID - Lánczky2016 ER - TY - JOUR AU - Rosen, J. M. AU - Jordan, C. T. PY - 2009 DA - 2009// TI - The increasing complexity of the cancer stem cell paradigm JO - Science. VL - 324 UR - https://doi.org/10.1126/science.1171837 DO - 10.1126/science.1171837 ID - Rosen2009 ER - TY - JOUR AU - Korkaya, H. AU - Liu, S. AU - Wicha, M. S. PY - 2011 DA - 2011// TI - Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots JO - Clin Cancer Res. VL - 17 UR - https://doi.org/10.1158/1078-0432.CCR-10-2743 DO - 10.1158/1078-0432.CCR-10-2743 ID - Korkaya2011 ER - TY - JOUR AU - Badve, S. AU - Nakshatri, H. PY - 2012 DA - 2012// TI - Breast-cancer stem cells-beyond semantics JO - Lancet Oncol. VL - 13 UR - https://doi.org/10.1016/S1470-2045(11)70191-7 DO - 10.1016/S1470-2045(11)70191-7 ID - Badve2012 ER - TY - JOUR AU - Pattabiraman, D. R. AU - Weinberg, R. A. PY - 2014 DA - 2014// TI - Tackling the cancer stem cells - what challenges do they pose? JO - Nat Rev Drug Discov. VL - 13 UR - https://doi.org/10.1038/nrd4253 DO - 10.1038/nrd4253 ID - Pattabiraman2014 ER - TY - JOUR AU - Nassar, D. AU - Blanpain, C. PY - 2016 DA - 2016// TI - Cancer Stem Cells: Basic Concepts and Therapeutic Implications JO - Annu Rev Pathol. VL - 11 UR - https://doi.org/10.1146/annurev-pathol-012615-044438 DO - 10.1146/annurev-pathol-012615-044438 ID - Nassar2016 ER - TY - JOUR AU - Foulkes, W. D. AU - Smith, I. E. AU - Reis-Filho, J. S. PY - 2010 DA - 2010// TI - Triple-negative breast cancer JO - N Engl J Med. VL - 363 UR - https://doi.org/10.1056/NEJMra1001389 DO - 10.1056/NEJMra1001389 ID - Foulkes2010 ER - TY - JOUR AU - Lin, L. AU - Fuchs, J. AU - Li, C. AU - Olson, V. AU - Bekaii-Saab, T. AU - Lin, J. PY - 2011 DA - 2011// TI - STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells JO - Biochem Biophys Res Commun. VL - 416 UR - https://doi.org/10.1016/j.bbrc.2011.10.112 DO - 10.1016/j.bbrc.2011.10.112 ID - Lin2011 ER - TY - JOUR AU - Schroeder, A. AU - Herrmann, A. AU - Cherryholmes, G. AU - Kowolik, C. AU - Buettner, R. AU - Pal, S. PY - 2014 DA - 2014// TI - Loss of androgen receptor expression promotes a stem-like cell phenotype in prostate cancer through STAT3 signaling JO - Cancer Res. VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-0594 DO - 10.1158/0008-5472.CAN-13-0594 ID - Schroeder2014 ER - TY - JOUR AU - Su, Y. J. AU - Lai, H. M. AU - Chang, Y. W. AU - Chen, G. Y. AU - Lee, J. L. PY - 2011 DA - 2011// TI - Direct reprogramming of stem cell properties in colon cancer cells by CD44 JO - EMBO J. VL - 30 UR - https://doi.org/10.1038/emboj.2011.211 DO - 10.1038/emboj.2011.211 ID - Su2011 ER - TY - JOUR AU - Chung, S. S. AU - Aroh, C. AU - Vadgama, J. V. PY - 2013 DA - 2013// TI - Constitutive activation of STAT3 signaling regulates hTERT and promotes stem cell-like traits in human breast cancer cells JO - PLoS One. VL - 8 UR - https://doi.org/10.1371/journal.pone.0083971 DO - 10.1371/journal.pone.0083971 ID - Chung2013 ER - TY - JOUR AU - Won, C. AU - Kim, B. H. AU - Yi, E. H. AU - Choi, K. J. AU - Kim, E. K. AU - Jeong, J. M. PY - 2015 DA - 2015// TI - Signal transducer and activator of transcription 3-mediated CD133 up-regulation contributes to promotion of hepatocellular carcinoma JO - Hepatology. VL - 62 UR - https://doi.org/10.1002/hep.27968 DO - 10.1002/hep.27968 ID - Won2015 ER - TY - JOUR AU - Gupta, P. B. AU - Chaffer, C. L. AU - Weinberg, R. A. PY - 2009 DA - 2009// TI - Cancer stem cells: mirage or reality? JO - Nat Med. VL - 15 UR - https://doi.org/10.1038/nm0909-1010 DO - 10.1038/nm0909-1010 ID - Gupta2009 ER - TY - JOUR AU - Singh, A. AU - Settleman, J. PY - 2010 DA - 2010// TI - EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer JO - Oncogene. VL - 29 UR - https://doi.org/10.1038/onc.2010.215 DO - 10.1038/onc.2010.215 ID - Singh2010 ER - TY - JOUR AU - Mani, S. A. AU - Guo, W. AU - Liao, M. J. AU - Eaton, E. N. AU - Ayyanan, A. AU - Zhou, A. Y. PY - 2008 DA - 2008// TI - The epithelial-mesenchymal transition generates cells with properties of stem cells JO - Cell. VL - 133 UR - https://doi.org/10.1016/j.cell.2008.03.027 DO - 10.1016/j.cell.2008.03.027 ID - Mani2008 ER - TY - JOUR AU - Morel, A. P. AU - Lièvre, M. AU - Thomas, C. AU - Hinkal, G. AU - Ansieau, S. AU - Puisieux, A. PY - 2008 DA - 2008// TI - Generation of breast cancer stem cells through epithelial-mesenchymal transition JO - PLoS One. VL - 3 UR - https://doi.org/10.1371/journal.pone.0002888 DO - 10.1371/journal.pone.0002888 ID - Morel2008 ER - TY - JOUR AU - Wang, S. S. AU - Jiang, J. AU - Liang, X. H. AU - Tang, Y. L. PY - 2015 DA - 2015// TI - Links between cancer stem cells and epithelial-mesenchymal transition JO - Onco Targets Ther. VL - 8 ID - Wang2015 ER - TY - JOUR AU - Vazquez-Santillan, K. AU - Melendez-Zajgla, J. AU - Jimenez-Hernandez, L. AU - Martínez-Ruiz, G. AU - Maldonado, V. PY - 2015 DA - 2015// TI - NF-κB signaling in cancer stem cells: a promising therapeutic target? JO - Cell Oncol (Dordr). VL - 38 UR - https://doi.org/10.1007/s13402-015-0236-6 DO - 10.1007/s13402-015-0236-6 ID - Vazquez-Santillan2015 ER - TY - JOUR AU - Tang, Y. AU - Kitisin, K. AU - Jogunoori, W. AU - Li, C. AU - Deng, C. X. AU - Mueller, S. C. PY - 2008 DA - 2008// TI - Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling JO - Proc Natl Acad Sci U S A. VL - 105 UR - https://doi.org/10.1073/pnas.0705395105 DO - 10.1073/pnas.0705395105 ID - Tang2008 ER - TY - JOUR AU - Gujral, T. S. AU - Chan, M. AU - Peshkin, L. AU - Sorger, P. K. AU - Kirschner, M. W. AU - MacBeath, G. PY - 2014 DA - 2014// TI - A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis JO - Cell. VL - 159 UR - https://doi.org/10.1016/j.cell.2014.10.032 DO - 10.1016/j.cell.2014.10.032 ID - Gujral2014 ER - TY - JOUR AU - Peñuelas, S. AU - Anido, J. AU - Prieto-Sánchez, R. M. AU - Folch, G. AU - Barba, I. AU - Cuartas, I. PY - 2009 DA - 2009// TI - TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma JO - Cancer Cell. VL - 15 UR - https://doi.org/10.1016/j.ccr.2009.02.011 DO - 10.1016/j.ccr.2009.02.011 ID - Peñuelas2009 ER - TY - JOUR AU - Liu, W. H. AU - Chen, M. T. AU - Wang, M. L. AU - Lee, Y. Y. AU - Chiou, G. Y. AU - Chien, C. S. PY - 2015 DA - 2015// TI - Cisplatin-selected resistance is associated with increased motility and stem-like properties via activation of STAT3/Snail axis in atypical teratoid/rhabdoid tumor cells JO - Oncotarget. VL - 6 ID - Liu2015 ER - TY - JOUR AU - Chung, S. S. AU - Giehl, N. AU - Wu, Y. AU - Vadgama, J. V. PY - 2014 DA - 2014// TI - STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits JO - Int J Oncol. VL - 44 UR - https://doi.org/10.3892/ijo.2013.2195 DO - 10.3892/ijo.2013.2195 ID - Chung2014 ER - TY - JOUR AU - Korkaya, H. AU - Kim, G. I. AU - Davis, A. AU - Malik, F. AU - Henry, N. L. AU - Ithimakin, S. PY - 2012 DA - 2012// TI - Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population JO - Mol Cell. VL - 47 UR - https://doi.org/10.1016/j.molcel.2012.06.014 DO - 10.1016/j.molcel.2012.06.014 ID - Korkaya2012 ER - TY - JOUR AU - Aghazadeh, S. AU - Yazdanparast, R. PY - 2017 DA - 2017// TI - Activation of STAT3/HIF-1α/Hes-1 axis promotes trastuzumab resistance in HER2-overexpressing breast cancer cells via down-regulation of PTEN JO - Biochim Biophys Acta. VL - 1861 UR - https://doi.org/10.1016/j.bbagen.2017.05.009 DO - 10.1016/j.bbagen.2017.05.009 ID - Aghazadeh2017 ER - TY - JOUR AU - Zhou, J. AU - Wulfkuhle, J. AU - Zhang, H. AU - Gu, P. AU - Yang, Y. AU - Deng, J. PY - 2007 DA - 2007// TI - Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance JO - Proc Natl Acad Sci U S A. VL - 104 UR - https://doi.org/10.1073/pnas.0702596104 DO - 10.1073/pnas.0702596104 ID - Zhou2007 ER - TY - JOUR AU - Moon, S. H. AU - Kim, D. K. AU - Cha, Y. AU - Jeon, I. AU - Song, J. AU - Park, K. S. PY - 2013 DA - 2013// TI - PI3K/Akt and Stat3 signaling regulated by PTEN control of the cancer stem cell population, proliferation and senescence in a glioblastoma cell line JO - Int J Oncol. VL - 42 UR - https://doi.org/10.3892/ijo.2013.1765 DO - 10.3892/ijo.2013.1765 ID - Moon2013 ER - TY - JOUR AU - Fantozzi, A. AU - Gruber, D. C. AU - Pisarsky, L. AU - Heck, C. AU - Kunita, A. AU - Yilmaz, M. PY - 2014 DA - 2014// TI - VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation JO - Cancer Res. VL - 74 UR - https://doi.org/10.1158/0008-5472.CAN-13-1641 DO - 10.1158/0008-5472.CAN-13-1641 ID - Fantozzi2014 ER - TY - JOUR AU - Jinushi, M. AU - Chiba, S. AU - Yoshiyama, H. AU - Masutomi, K. AU - Kinoshita, I. AU - Dosaka-Akita, H. PY - 2011 DA - 2011// TI - Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells JO - Proc Natl Acad Sci U S A. VL - 108 UR - https://doi.org/10.1073/pnas.1106645108 DO - 10.1073/pnas.1106645108 ID - Jinushi2011 ER - TY - JOUR AU - Yang, J. AU - Liao, D. AU - Chen, C. AU - Liu, Y. AU - Chuang, T. H. AU - Xiang, R. PY - 2013 DA - 2013// TI - Tumor-associated macrophages regulate murine breast cancer stem cells through a novel paracrine EGFR/Stat3/Sox-2 signaling pathway JO - Stem Cells. VL - 31 UR - https://doi.org/10.1002/stem.1281 DO - 10.1002/stem.1281 ID - Yang2013 ER - TY - JOUR AU - Attarha, S. AU - Roy, A. AU - Westermark, B. AU - Tchougounova, E. PY - 2017 DA - 2017// TI - Mast cells modulate proliferation, migration and stemness of glioma cells through downregulation of GSK3β expression and inhibition of STAT3 activation JO - Cell Signal. VL - 37 UR - https://doi.org/10.1016/j.cellsig.2017.06.004 DO - 10.1016/j.cellsig.2017.06.004 ID - Attarha2017 ER - TY - JOUR AU - Islam, M. AU - Sharma, S. AU - Teknos, T. N. PY - 2014 DA - 2014// TI - RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3 JO - PLoS One. VL - 9 UR - https://doi.org/10.1371/journal.pone.0088527 DO - 10.1371/journal.pone.0088527 ID - Islam2014 ER - TY - JOUR AU - Zhao, C. AU - Li, H. AU - Lin, H. J. AU - Yang, S. AU - Lin, J. AU - Liang, G. PY - 2016 DA - 2016// TI - Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism JO - Trends Pharmacol Sci. VL - 37 UR - https://doi.org/10.1016/j.tips.2015.10.001 DO - 10.1016/j.tips.2015.10.001 ID - Zhao2016 ER - TY - JOUR AU - Yang, F. AU - Van Meter, T. E. AU - Buettner, R. AU - Hedvat, M. AU - Liang, W. AU - Kowolik, C. M. PY - 2008 DA - 2008// TI - Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas JO - Mol Cancer Ther. VL - 7 UR - https://doi.org/10.1158/1535-7163.MCT-08-0138 DO - 10.1158/1535-7163.MCT-08-0138 ID - Yang2008 ER - TY - JOUR AU - Nefedova, Y. AU - Nagaraj, S. AU - Rosenbauer, A. AU - Muro-Cacho, C. AU - Sebti, S. M. AU - Gabrilovich, D. I. PY - 2005 DA - 2005// TI - Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway JO - Cancer Res. VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-05-0529 DO - 10.1158/0008-5472.CAN-05-0529 ID - Nefedova2005 ER - TY - JOUR AU - Yang, A. AU - Kaghad, M. AU - Wang, Y. AU - Gillett, E. AU - Fleming, M. D. AU - Dötsch, V. PY - 1998 DA - 1998// TI - p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities JO - Mol Cell. VL - 2 UR - https://doi.org/10.1016/S1097-2765(00)80275-0 DO - 10.1016/S1097-2765(00)80275-0 ID - Yang1998 ER - TY - JOUR AU - Chu, W. K. AU - Dai, P. M. AU - Li, H. L. AU - Chen, J. K. PY - 2008 DA - 2008// TI - Transcriptional activity of the DeltaNp63 promoter is regulated by STAT3 JO - J Biol Chem. VL - 283 UR - https://doi.org/10.1074/jbc.M800183200 DO - 10.1074/jbc.M800183200 ID - Chu2008 ER - TY - JOUR AU - Rufini, S. AU - Lena, A. M. AU - Cadot, B. AU - Mele, S. AU - Amelio, I. AU - Terrinoni, A. PY - 2011 DA - 2011// TI - The sterile alpha-motif (SAM) domain of p63 binds in vitro monoasialoganglioside (GM1) micelles JO - Biochem Pharmacol. VL - 82 UR - https://doi.org/10.1016/j.bcp.2011.07.087 DO - 10.1016/j.bcp.2011.07.087 ID - Rufini2011 ER - TY - JOUR AU - Sayan, B. S. AU - Sayan, A. E. AU - Yang, A. L. AU - Aqeilan, R. I. AU - Candi, E. AU - Cohen, G. M. PY - 2007 DA - 2007// TI - Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis JO - Proc Natl Acad Sci U S A. VL - 104 UR - https://doi.org/10.1073/pnas.0700761104 DO - 10.1073/pnas.0700761104 ID - Sayan2007 ER - TY - JOUR AU - Mills, A. A. AU - Zheng, B. AU - Wang, X. J. AU - Vogel, H. AU - Roop, D. R. AU - Bradley, A. PY - 1999 DA - 1999// TI - p63 is a p53 homologue required for limb and epidermal morphogenesis JO - Nature. VL - 398 UR - https://doi.org/10.1038/19531 DO - 10.1038/19531 ID - Mills1999 ER - TY - JOUR AU - Yang, A. AU - Schweitzer, R. AU - Sun, D. AU - Kaghad, M. AU - Walker, N. AU - Bronson, R. T. PY - 1999 DA - 1999// TI - p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development JO - Nature. VL - 398 UR - https://doi.org/10.1038/19539 DO - 10.1038/19539 ID - Yang1999 ER - TY - JOUR AU - Pignon, J. C. AU - Grisanzio, C. AU - Geng, Y. AU - Song, J. AU - Shivdasani, R. A. AU - Signoretti, S. PY - 2013 DA - 2013// TI - p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia JO - Proc Natl Acad Sci U S A. VL - 110 UR - https://doi.org/10.1073/pnas.1221216110 DO - 10.1073/pnas.1221216110 ID - Pignon2013 ER - TY - JOUR AU - Liu, K. AU - Jiang, M. AU - Lu, Y. AU - Chen, H. AU - Sun, J. AU - Wu, S. PY - 2013 DA - 2013// TI - Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells JO - Cell Stem Cell. VL - 12 UR - https://doi.org/10.1016/j.stem.2013.01.007 DO - 10.1016/j.stem.2013.01.007 ID - Liu2013 ER - TY - JOUR AU - Sethi, I. AU - Sinha, S. AU - Buck, M. J. PY - 2014 DA - 2014// TI - Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes JO - BMC Genomics. VL - 15 UR - https://doi.org/10.1186/1471-2164-15-1042 DO - 10.1186/1471-2164-15-1042 ID - Sethi2014 ER - TY - JOUR AU - Wu, M. AU - Wang, B. AU - Gil, J. AU - Sabo, E. AU - Miller, L. AU - Gan, L. PY - 2003 DA - 2003// TI - p63 and TTF-1 immunostaining. A useful marker panel for distinguishing small cell carcinoma of lung from poorly differentiated squamous cell carcinoma of lung JO - Am J Clin Pathol. VL - 119 UR - https://doi.org/10.1309/P5ABR5KQ89RNJTFH DO - 10.1309/P5ABR5KQ89RNJTFH ID - Wu2003 ER - TY - STD TI - Chakrabarti R, Wei Y, Hwang J, Hang X, Andres Blanco M. Choudhury A, et al. ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling. Nat Cell Biol. 2014; 16. 1004-15:1–13. ID - ref168 ER - TY - JOUR AU - Koster, M. I. AU - Lu, S. L. AU - White, L. D. AU - Wang, X. J. AU - Roop, D. R. PY - 2006 DA - 2006// TI - Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression JO - Cancer Res. VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-06-0027 DO - 10.1158/0008-5472.CAN-06-0027 ID - Koster2006 ER - TY - JOUR AU - Wei, W. AU - Tweardy, D. J. AU - Zhang, M. AU - Zhang, X. AU - Landua, J. AU - Petrovic, I. PY - 2014 DA - 2014// TI - STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer JO - Stem Cells. VL - 32 UR - https://doi.org/10.1002/stem.1752 DO - 10.1002/stem.1752 ID - Wei2014 ER - TY - JOUR AU - Hajimoradi, M. AU - Mohammad Hassan, Z. AU - Ebrahimi, M. AU - Soleimani, M. AU - Bakhshi, M. AU - Firouzi, J. PY - 2016 DA - 2016// TI - STAT3 is Overactivated in Gastric Cancer Stem-Like Cells JO - Cell J. VL - 17 ID - Hajimoradi2016 ER - TY - JOUR AU - Sriuranpong, V. AU - Park, J. I. AU - Amornphimoltham, P. AU - Patel, V. AU - Nelkin, B. D. AU - Gutkind, J. S. PY - 2003 DA - 2003// TI - Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system JO - Cancer Res. VL - 63 ID - Sriuranpong2003 ER - TY - JOUR AU - Thiagarajan, P. S. AU - Zheng, Q. AU - Bhagrath, M. AU - Mulkearns-Hubert, E. E. AU - Myers, M. G. AU - Lathia, J. D. PY - 2017 DA - 2017// TI - STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance JO - Endocr Relat Cancer. VL - 24 UR - https://doi.org/10.1530/ERC-16-0349 DO - 10.1530/ERC-16-0349 ID - Thiagarajan2017 ER - TY - JOUR AU - Chu, W. K. AU - Lee, K. C. AU - Chow, S. E. AU - Chen, J. K. PY - 2006 DA - 2006// TI - Dual regulation of the DeltaNp63 transcriptional activity by DeltaNp63 in human nasopharyngeal carcinoma cell JO - Biochem Biophys Res Commun. VL - 342 UR - https://doi.org/10.1016/j.bbrc.2006.02.111 DO - 10.1016/j.bbrc.2006.02.111 ID - Chu2006 ER - TY - JOUR AU - Hsueh, Y. J. AU - Chen, H. C. AU - Chu, W. K. AU - Cheng, C. C. AU - Kuo, P. C. AU - Lin, L. Y. PY - 2011 DA - 2011// TI - STAT3 regulates the proliferation and differentiation of rabbit limbal epithelial cells via a ΔNp63-dependent mechanism JO - Invest Ophthalmol Vis Sci. VL - 52 UR - https://doi.org/10.1167/iovs.10-6103 DO - 10.1167/iovs.10-6103 ID - Hsueh2011 ER - TY - JOUR AU - Ripamonti, F. AU - Albano, L. AU - Rossini, A. AU - Borrelli, S. AU - Fabris, S. AU - Mantovani, R. PY - 2013 DA - 2013// TI - EGFR through STAT3 modulates ΔN63α expression to sustain tumor-initiating cell proliferation in squamous cell carcinomas JO - J Cell Physiol. VL - 228 UR - https://doi.org/10.1002/jcp.24238 DO - 10.1002/jcp.24238 ID - Ripamonti2013 ER - TY - JOUR AU - Ma, J. AU - Meng, Y. AU - Kwiatkowski, D. J. AU - Chen, X. AU - Peng, H. AU - Sun, Q. PY - 2010 DA - 2010// TI - Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade JO - J Clin Invest. VL - 120 UR - https://doi.org/10.1172/JCI37964 DO - 10.1172/JCI37964 ID - Ma2010 ER - TY - JOUR AU - King, K. E. AU - Ponnamperuma, R. M. AU - Allen, C. AU - Lu, H. AU - Duggal, P. AU - Chen, Z. PY - 2008 DA - 2008// TI - The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kappaB pathway to modulate epithelial cell growth JO - Cancer Res. VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-07-6123 DO - 10.1158/0008-5472.CAN-07-6123 ID - King2008 ER - TY - JOUR AU - Yang, X. PY - 2011 DA - 2011// TI - Lu H, Yan B, Romano RA, Bian Y, Friedman J, et al. ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation JO - Cancer Res. VL - 71 UR - https://doi.org/10.1158/0008-5472.CAN-10-3445 DO - 10.1158/0008-5472.CAN-10-3445 ID - Yang2011 ER - TY - JOUR AU - Senoo, M. AU - Matsumura, Y. AU - Habu, S. PY - 2002 DA - 2002// TI - TAp63gamma (p51A) and dNp63alpha (p73L), two major isoforms of the p63 gene, exert opposite effects on the vascular endothelial growth factor (VEGF) gene expression JO - Oncogene. VL - 21 UR - https://doi.org/10.1038/sj.onc.1205330 DO - 10.1038/sj.onc.1205330 ID - Senoo2002 ER - TY - JOUR AU - Stacy, A. J. AU - Craig, M. P. AU - Sakaram, S. AU - Kadakia, M. PY - 2017 DA - 2017// TI - ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition JO - Oncotarget. VL - 8 UR - https://doi.org/10.18632/oncotarget.13797 DO - 10.18632/oncotarget.13797 ID - Stacy2017 ER - TY - JOUR AU - Sasaki, Y. AU - Ishida, S. AU - Morimoto, I. AU - Yamashita, T. AU - Kojima, T. AU - Kihara, C. PY - 2002 DA - 2002// TI - The p53 family member genes are involved in the Notch signal pathway JO - J Biol Chem. VL - 277 UR - https://doi.org/10.1074/jbc.M108080200 DO - 10.1074/jbc.M108080200 ID - Sasaki2002 ER - TY - JOUR AU - Su, X. AU - Napoli, M. AU - Abbas, H. A. AU - Venkatanarayan, A. AU - Bui, N. H. B. AU - Coarfa, C. PY - 2017 DA - 2017// TI - TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway JO - Oncogene. VL - 36 UR - https://doi.org/10.1038/onc.2016.388 DO - 10.1038/onc.2016.388 ID - Su2017 ER -