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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: Mitochonic acid 5 activates the MAPK–ERK–yap signaling pathways to protect mouse microglial BV-2 cells against TNFα-induced apoptosis via increased Bnip3-related mitophagy

Fig. 1

MA-5 reduces TNFα-induced apoptosis in mouse microglial BV-2 cells in a dose-dependent manner. a The MTT assay was used to evaluate the cellular viability. b The caspase-3 activity indicates that TNFα promoted BV-2 cell death. c and d The TUNEL assay was used to measure cellular apoptosis. *p < 0.05 vs. control (Ctrl) group; #p < 0.05 vs. TNFα group

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