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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1

Fig. 4

miR-17-induced steatosis depends on the expression of CYP7A1. a Downregulation of CYP7A1 by siRNA transfection in HepG2 cells. b CYP7A1 siRNA transfection promotes steatosis in HepG2 cells. c Upregulation of CYP7A1 by CYP7A1 expression construct transfection in miR-17 HepG2 cells. d Re-introduction of CYP7A1 into miR-17 HepG2 cells could partially alleviate steatosis

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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