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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Osthole improves collagen-induced arthritis in a rat model through inhibiting inflammation and cellular stress

Fig. 5

Osthole inhibits IL-1β-induced activation of NF-κB and MAPK pathway. a SW982 cells were treated with 25, 50 and 100 μM osthole and 10 ng/ml IL-1β for 48 h. The levels of IκBα, p65, IKKαβ and phosphorylated levels were detected by immunoblotting. β-Actin was chosen as a loading control. The result is representative of three experiments. b SW982 cells were treated with 25, 50 and 100 μM osthole and 10 ng/ml IL-1β for 48 h. The levels of ERK1/2, JNK and p38 and phosphorylated levels were detected by immunoblotting. β-Actin was chosen as a loading control. The result is representative of three experiments

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