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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: MicroRNA-488 inhibits tongue squamous carcinoma cell invasion and EMT by directly targeting ATF3

Fig. 3

ATF3 is a direct target of miR-488. TCA8113 cells were transfected with miR-488 mimic or inhibitor for 48 h. a Schematic representation of ATF3 3’UTRs showing putative miRNA target site. b The analysis of the relative luciferase activities of ATF3-WT and ATF3-MUT. c The mRNA and protein expressions of ATF3 were determined via quantitative RT-PCR and western blot, respectively. All data are presented as means ± SEM, n = 6. ##p < 0.01, ###p < 0.001 vs. miR-NC

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