Fig. 3
From: LAMP3 plays an oncogenic role in osteosarcoma cells partially by inhibiting TP53
TP53 was upregulated and partially reversed the effect of LAMP3 on osteosarcoma (OS) cell viability and apoptosis. a – Quantitative RT-PCR results showing the mRNA levels of apoptotic genes after knockdown of LAMP3. b – Western blot confirmed the knockdown efficiency of TP53 with β-actin as the loading control. c – Apoptosis assay results showing that the percentage of apoptotic cells was decreased after inhibition of TP53 in siLAMP3 cells. d – MTT assay results showing that OS cell viability was increased after the inhibition of TP53 in siLAMP3 cells. *p < 0.05, **p < 0.01, ***p < 0.001, n = 3