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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: Inhibition of inflammation using diacerein markedly improved renal function in endotoxemic acute kidney injured mice

Fig. 1

LPS induced IL-1β level in mouse kidney tissues. a Interleukin-1β (IL-1β) mRNA expression was analyzed in kidney tissues from control or lipopolysaccharide (LPS)-treated mice by real-time PCR at the times as indicated. LPS time-dependently increased the IL-1β mRNA expression. b ELISA analysis showing time-dependent increase of renal concentrations of IL-1β after LPS treatment for 72 h compared with control group. **P < 0.01 vs. control, n = 8 in each group. c and d Immunohistochemical protein expression of IL-1β in renal cortex (c) and medulla (d) of mice after 72 h of LPS treatment (magnification, 200×). Arrows indicate the positive staining area of IL-1β

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