Skip to main content

Advertisement

Table 1 EGFR/MSI1 mRNA expression and clinicopathological features of ESCC patients

From: WNT and NOTCH signaling pathways as activators for epidermal growth factor receptor in esophageal squamous cell carcinoma

  Total EGFR/ MSI1 over expression EGFR/ MSI1 under expression EGFR/ MSI1 normal expression EGFR over expression MSI1 over expression P- Value
Patients 48 7(14.6%) 2(4.2%) 14(29.2%) 12(25%) 12(25%)  
Mean age (mean ± SD) 61.85 ± 12.33 55.86 ± 5.65 42.50 ± 6.50 66.43 ± 2.30 63.17 ± 2.36 60.58 ± 4.29  
Size (mean ± SD) 4.23 ± 1.91 3.50 ± 0.58 3.75 ± 1.75 4.20 ± 0.36 4.29 ± 0.58 4.88 ± 0.73  
Sex 0.553
 Male 28(58.3%) 5(71.4%) 8(57.1%) 8(66.7%) 7(58.3%)  
 Female 20(41.7%) 2(28.6%) 2(100%) 6(42.9%) 4(33.3%) 5(41.7%)  
Location 0.226
 Lower 21(43.8%) 2(28.6%) 8(57.1%) 4(33.3%) 6(50%)  
 Middle 27(56.2%) 5(71.4%) 2(100%) 6(42.9%) 8(66.7%) 6(50%)  
Grade 0.020
 Poorly differentiated 8(16.7%) 2(28.6%) 2(100%) 1(7.1%) 1(8.3%) 1(8.3%)  
 Moderately differentiated 31(64.6%) 5(71.4%) 11(78.6%) 8(66.7%) 7(58.3%)  
 Well differentiated 9(18.8%) 2(14.3%) 3(25%) 4(33.3%)  
Lymph node metastasis 0.702
 Yes 22(45.8%) 2(28.6%) 1(50%) 8(57.1%) 4(33.3%) 6(50%)  
 No 26(54.2%) 5(71.4%) 1(50%) 6(42.9%) 8(66.7%) 6(50%)  
Stage 0.763
 I/II 29(60.4%) 5(71.4%) 1(50%) 7(50%) 9(75%) 7(58.3%)  
 III/IV 19(39.6%) 2(28.6%) 1(50%) 7(50%) 3(25%) 5(41.7%)  
Depth of tumor invasion (T) 0.292
 T1 1(2.1%) 1(14.3%)  
 T2 7(14.6%) 2(14.3%) 4(33.3%) 1(8.3%)  
 T3 40(83.3%) 6(85.7%) 2(100%) 12(85.7%) 8(66.7%) 11(91.7%)  
  1. Bold values indicate significant correlation between mRNA expression and clinicopathological features