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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Elevated IL-33 promotes expression of MMP2 and MMP9 via activating STAT3 in alveolar macrophages during LPS-induced acute lung injury

Fig. 5

Effect of STAT3 knockdown on IL-33-induced expression of MMP2 and MMP9 in NR8383 cells. (a and b) Levels of MMP2 (a) and MMP9 (b) in the medium at 24 h after IL-33 treatment in NR8383 cells with or without knockdown of STAT3. (c-f) mRNA levels of MMP2 (c), MMP9 (d), STAT3 (e), and STAT1 (f) at 24 h after IL-33 treatment in NR8383 cells with or without knockdown of STAT3. Data are shown as means±SD (three independent repeats). The relative mRNA level was normalized to the siCtrl/PBS group. Two-way ANOVA was used in the statistical analyses. * p < 0.05, *** p < 0.001

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