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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Identification and validation of NOLC1 as a potential target for enhancing sensitivity in multidrug resistant non-small cell lung cancer cells

Fig. 5

NOLC1 knockdown significantly promoted cell apoptosis in A549/MDR cells. a Flow cytometry analysis of A549/MDR cells stained with Annexin V and PI. The effect of siRNA-mediated NOLC1 knockdown on apoptosis was analyzed. Data were expressed as means ± SD of at least three experiments. b Hoechst staining assay was used to analyze the percentage of cells with fragmented nuclei in A549/MDR cells. **p < 0.01 versus A549/MDR + NC

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