Skip to main content

Table 2 Cytotoxicity of drugs in A549/MDR cell after siNOLC1 transfection

From: Identification and validation of NOLC1 as a potential target for enhancing sensitivity in multidrug resistant non-small cell lung cancer cells

Drug NC-IC50 (μg/ml) siNOLC1-IC50 (μg/ml) RI
5-fluorouracil 130.53 75.71 0.58
Paclitaxel 83.52 17.54 0.21
Mitomycin 8.64 3.89 0.45
Vinorelbine Tartrate 12.40 18.47 1.49
Cisplatin 33.00 10.89 0.33
Gemcitabine Hydrochloride 19.05 7.05 0.37
  1. IC50 50% inhibitory concentration, RI resistance index, DDP Cisplatin, MDR multidrug resistance